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KH Domain

Known as: K Homology Domain 
First identified in human hnRNPK protein, the conserved KH Domain of around 45-70 amino acids is present in a variety of nucleic acid-binding… 
National Institutes of Health

Related topics

Related topics

7 relations
FMR1 protein, humanFUBP1 protein, humanKH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 1NOVA1 protein, human

Papers overview

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2005
2005
Structure and RNA binding of the third KH domain of poly(C)-binding protein 1
Poly(C)-binding proteins (CPs) are important regulators of mRNA stability and translational regulation. They recognize C-rich RNA… 
Highly Cited
2005
Highly Cited
2005
Role for RNA-Binding Proteins Implicated in Pathogenic Development of Ustilago maydis
ABSTRACT Ustilago maydis causes smut disease on corn. Successful infection depends on a number of morphological transitions, such… 
Highly Cited
2004
Highly Cited
2004
The STAR/Maxi-KH domain protein GLD-1 mediates a developmental switch in the translational control of C. elegans PAL-1
Translational control is an essential mechanism of gene control utilized throughout development, yet the molecular mechanisms… 
2001
2001
An in vitro-selected RNA-binding site for the KH domain protein PSI acts as a splicing inhibitor element.
P element somatic inhibitor (PSI) is a 97-kDa RNA-binding protein with four KH motifs that is involved in the inhibition of… 
Highly Cited
2000
Highly Cited
2000
MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M
ABSTRACT p53, a tumor suppressor, inhibits cell proliferation by inducing cellular genes involved in the regulation of the cell… 
Highly Cited
1997
Highly Cited
1997
Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA.
The 5' noncoding region of the poliovirus genome contains RNA structures important for replication and translation. Here we show… 
Highly Cited
1997
Highly Cited
1997
Specificity and Determinants of Sam68 RNA Binding
Sam68, a specific target of the Src tyrosine kinase in mitosis, possesses features common to RNA-binding proteins, including a K… 
Highly Cited
1996
Highly Cited
1996
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos
Highly Cited
1995
Highly Cited
1995
Localized Bicaudal‐C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1
The Bicaudal-C (Bic-C) gene of Drosophila melanogaster is required for correct targeting of the migrating anterior follicle cells… 
Highly Cited
1994
Highly Cited
1994
Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome
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