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NOVA1 protein, human

Known as: Onconeural Ventral Antigen-1, NOVA1, Ri Antigen 
RNA-binding protein Nova-1 (510 aa, ~52 kDa) is encoded by the human NOVA1 gene. This protein is involved in sequence-specific RNA binding.
National Institutes of Health

Related topics

Related topics

15 relations
Breast CarcinomaCell NucleusCell SurvivalHomo sapiens

Broader (1)

RNA-Binding Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer
Alternative splicing is dysregulated in cancer and the reactivation of telomerase involves the splicing of TERT transcripts to… 
Highly Cited
2014
Highly Cited
2014
MiR-181b-5p Downregulates NOVA1 to Suppress Proliferation, Migration and Invasion and Promote Apoptosis in Astrocytoma
MicroRNAs (miRNAs) are small, short noncoding RNAs that modulate the expression of numerous genes by targeting their mRNA… 
Highly Cited
2014
Highly Cited
2014
Nova1 is a master regulator of alternative splicing in pancreatic beta cells
Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human… 
Highly Cited
2012
Highly Cited
2012
The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by… 
Highly Cited
2008
Highly Cited
2008
Post-transcriptional Regulation of Neuro-oncological Ventral Antigen 1 by the Neuronal RNA-binding Proteins ELAV*
Alternative splicing of pre-mRNAs plays an important role in generating biological and functional diversity. Neuro-oncological… 
Highly Cited
2007
Highly Cited
2007
Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements
Knowledge of the functional cis-regulatory elements that regulate constitutive and alternative pre-mRNA splicing is fundamental… 
2007
2007
Correction: Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements
Knowledge of the functional cis-regulatory elements that regulate constitutive and alternative pre-mRNA splicing is fundamental… 
Highly Cited
1998
Highly Cited
1998
The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia.
Paraneoplastic opsoclonus myoclonus ataxia (POMA) is a neurologic disorder thought to be mediated by an autoimmune attack against… 
Highly Cited
1997
Highly Cited
1997
The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo
Nova-1, an autoantigen in paraneoplastic opsoclonus myoclonus ataxia (POMA), a disorder associated with breast cancer and motor… 
Highly Cited
1996
Highly Cited
1996
The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies
Nova-1, a protein expressed in tumors and neurons, is a target antigen in a human paraneoplastic motor disorder [paraneoplastic… 
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