Janus kinase 2

Known as: JAK2 Protein Tyrosine Kinase, Janus Kinase 2 [Chemical/Ingredient], JAK-2 Protein Tyrosine Kinase 
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as… (More)

Topic mentions per year

Topic mentions per year

1993-2017
010020019932017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
BACKGROUND Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular… (More)
  • figure 1
  • figure 2
  • table 1
  • table 1
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The limited vessel-forming capacity of infused endothelial progenitor cells (EPCs) into patients with cardiovascular dysfunction… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The Bcr-Abl tyrosine kinase is the causative factor in most chronic myelogenous leukemia (CML) patients. We have shown that Bcr… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Myeloproliferative disorders are clonal haematopoietic stem cell malignancies characterized by independency or hypersensitivity… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND Polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis are clonal myeloproliferative disorders… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND Human myeloproliferative disorders form a range of clonal haematological malignant diseases, the main members of which… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM) are clonal disorders… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
We show that Janus kinase 2 (JAK2), and more specifically just its intact N-terminal domain, binds to the erythropoietin receptor… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Erythropoietin (EPO) regulates the proliferation and differentiation of erythroid cells through interaction with its receptor… (More)
Is this relevant?