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JAK3 gene

Known as: Janus kinase 3, tyrosine-protein kinase JAK3, JANUS KINASE, LEUKOCYTE 
This gene plays a role in signal transduction.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
OBJECTIVE To assess the efficacy and safety of decernotinib (VX-509), an oral selective inhibitor of JAK-3, in patients with… Expand
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Highly Cited
2015
Highly Cited
2015
OBJECTIVE To assess the efficacy and safety of oral decernotinib (VX-509; Vertex Pharmaceuticals) monotherapy in a 12-week… Expand
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE S100A4 has been shown to be increased in osteoarthritic (OA) cartilage and to stimulate chondrocytes to produce matrix… Expand
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Highly Cited
2006
Highly Cited
2006
The system created in noncentral relativistic nucleus-nucleus collisions possesses large orbital angular momentum. Because of… Expand
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Review
2005
Review
2005
CD4+CD25+ T regulatory (Treg) cells control immunologic tolerance to self-antigens and play a role in suppressing antitumor… Expand
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2002
2002
The protein tyrosine kinases JAKl and JAK2 are phosphorylated on tyrosine after the interaction of granulocyte colonystimulating… Expand
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2000
2000
Prodigiosins (Ps) represent a family of naturally occurring red pigments characterized by a common pyrrolylpyrromethene skeleton… Expand
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Review
1998
Review
1998
Both IL-15 and IL-2 are 14-15 kDa members of the four alpha-helical bundle family of cytokines that have T cell growth factor… Expand
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1998
1998
Insulin and insulin-like growth factor-1 (IGF-1) treatment of cells overexpressing the insulin receptor or the IGF-1 receptor… Expand
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1995
1995
Interleukin-13 (IL-13) and interleukin-4 (IL-4) are related in structure and function and are thought to share a common receptor… Expand
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