Insulin-Like Growth-Factor-Binding Proteins

Known as: IGF Binding Proteins, Somatomedin Binding Proteins, Insulin-Like Growth Factor Binding Proteins 
A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. Serum IGFBP levels… (More)
National Institutes of Health

Papers overview

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Review
2003
Review
2003
High-affinity interactions between insulin-like growth factors (IGF-I and IGF-II) and insulin-like growth factor-binding proteins… (More)
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Review
2002
Review
2002
In addition to their roles in IGF transport, the six IGF-binding proteins (IGFBPs) regulate cell activity in various ways. By… (More)
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Highly Cited
2002
Highly Cited
2002
Plasma levels of insulin-like growth factor I (IGF-I) have been associated with risk of several cancers. Although protein-calorie… (More)
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Review
2000
Review
2000
Interest in the role of the insulin-like growth factor (IGF) axis in growth control and carcinogenesis has recently been… (More)
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Review
2000
Review
2000
The insulin-like growth factors (IGFs) are mitogens that play a pivotal role in regulating cell proliferation, differentiation… (More)
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Review
1999
Review
1999
Over the last decade, the concept of an IGFBP family has been well accepted, based on structural similarities and on functional… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Insulin-like growth factor-I (IGF-I) is a potent mitogen for normal and neoplastic cells, whereas IGF-binding protein… (More)
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Review
1998
Review
1998
The insulin-like growth factors (IGF) stimulate growth in multiple connective tissue cell types. The capacity of IGF-I and -II to… (More)
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Highly Cited
1988
Highly Cited
1988
The serum levels of 34K insulin-like growth factor (IGF)-binding protein were measured by RIA in 88 type 1 diabetic patients, 9… (More)
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Highly Cited
1986
Highly Cited
1986
A nitrocellulose gel transfer technique has been adapted to study the insulin-like growth factor (IGF) binding proteins of human… (More)
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