Immunoglobulins

Known as: IG, NOS, Immunoglobulins / Antibodies, Immunoglobulin 
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy… (More)
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (28)

40 ML bezlotoxumab 25 MG/ML InjectionBT088 immunoglobulin, humanFREP4 protein, Biomphalaria glabrataGV 523
(More)

Broader (3)

AntibodiesGlobulinsProteins
Cytomegalovirus immune globulin given:Vol:Pt:^Patient:QnIGLCOR22-1 geneImmunoglobulin Heavy ChainsImmunoglobulin Light Chains
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The impact of glycosylation on the biological function and structure of human immunoglobulins.
Immunoglobulins are the major secretory products of the adaptive immune system. Each is characterized by a distinctive set of… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health problem. Detailed analyses of HCV… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 6
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Follicular B Helper T Cells Express Cxc Chemokine Receptor 5, Localize to B Cell Follicles, and Support Immunoglobulin Production
Chemokines and their receptors have been identified as major regulators controlling the functional organization of secondary… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins.
Rheumatoid arthritis is a common and debilitating autoimmune disease whose cause and mechanism remain a mystery. We recently… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.
Toxic epidermal necrolysis (TEN, Lyell's syndrome) is a severe adverse drug reaction in which keratinocytes die and large… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
Human follicular B cell lymphomas possess a t(14;18) interchromosomal translocation that juxtaposes the putative proto-oncogene… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Canonical structures for the hypervariable regions of immunoglobulins.
We have analysed the atomic structures of Fab and VL fragments of immunoglobulins to determine the relationship between their… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
A new member of the immunoglobulin superfamily—CTLA-4
The immunoglobulin superfamily is a group of proteins, each made of one or several domains sharing key structural features with… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
To characterize proteins that bind to the immunoglobulin (Ig) heavy chain and the kappa light chain enhancers, an electrophoretic… (More)
Is this relevant?
Highly Cited
1972
Highly Cited
1972
The fluid mosaic model of the structure of cell membranes.
A fluid mosaic model is presented for the gross organization and structure of the proteins and lipids of biological membranes… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 6
  • figure 7
Is this relevant?