Immunoglobulin Idiotypes

Known as: Idiotype, Immunoglobulin, Idiotype, idiotypes 
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
PURPOSE The unique immunoglobulin idiotype (Id) expressed by each B-cell lymphoma is a target for immunotherapy. Vaccination with… (More)
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Highly Cited
1997
Highly Cited
1997
The surface Ig on each B-cell lymphoma has unique portions (idiotypes), which can be recognized by the immune system. In this… (More)
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Highly Cited
1996
Highly Cited
1996
The idiotype of the Ig expressed by a B-cell malignancy (Id) can serve as a unique tumor-specific antigen and as a model for… (More)
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Highly Cited
1995
Highly Cited
1995
The idiotype of myeloma immunoglobulin can be used as a unique tumour-specific antigen. We tested the hypothesis that tumour… (More)
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Highly Cited
1993
Highly Cited
1993
TO produce a vaccine against cancer, antigens must be found that are preferentially expressed by tumour cells and can induce an… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The idiotypic determinants of the surface immunoglobulin of a B-cell lymphoma can serve as a clonal tumor-specific… (More)
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Highly Cited
1990
Highly Cited
1990
The proximate cause of autoantibodies characteristic of systemic autoimmune diseases has been controversial. One hypothesis is… (More)
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Highly Cited
1985
Highly Cited
1985
We studied two patients with malignant B-cell lymphoma that manifested resistance to the therapeutic effects of anti-idiotype… (More)
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1980
1980
Tumour-specific antiserum was raised in sheep against idiotypic determinants on the surface immunoglobulin of neoplastic… (More)
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1975
1975
The ability of thymus-derived lymphocytes (T cells) from BALB/c mice to recognize the individually specific antigenic… (More)
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