Imipramine

Known as: 3-(5H-DIBENZO[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, 10,11-dihydro-N,N-Dimethyl-5H-dibenz[b,F]azepine-5-propanamine 
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces… (More)

Topic mentions per year

Topic mentions per year

1955-2018
010020019552017

Papers overview

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Highly Cited
2006
Highly Cited
2006
To better understand the molecular mechanisms of depression and antidepressant action, we administered chronic social defeat… (More)
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Highly Cited
2005
Highly Cited
2005
Antidepressants increase proliferation of neuronal progenitor cells and expression of brain-derived neurotrophic factor (BDNF) in… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Panic disorder (PD) may be treated with drugs, psychosocial intervention, or both, but the relative and combined… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE The authors examined gender differences in treatment response to sertraline, a selective serotonin reuptake inhibitor… (More)
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Highly Cited
1997
Highly Cited
1997
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  • Drug metabolism and disposition: the biological…
  • 1997
The nonspecific, noncovalent binding of three drugs, imipramine, warfarin, and propranolol, to pooled human and animal liver… (More)
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Highly Cited
1996
Highly Cited
1996
The present study demonstrates that chronic, but not acute, adminstration of several different classes of antidepressants… (More)
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Highly Cited
1988
Highly Cited
1988
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus… (More)
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Highly Cited
1987
Highly Cited
1987
To investigate whether an elevated plus-maze consisting of two open and two closed arms could be used as a model of anxiety in… (More)
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Highly Cited
1983
Highly Cited
1983
We have isolated 145 fertile mutants of C. elegans that are defective in egg laying and have characterized 59 of them genetically… (More)
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Highly Cited
1978
Highly Cited
1978
Rats and mice when forced to swim in a restricted space will rapidly cease attempts to escape and become immobile. Previous… (More)
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