Skip to search formSkip to main contentSkip to account menu

Imipramine

Known as: 3-(5H-DIBENZO[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, 10,11-dihydro-N,N-Dimethyl-5H-dibenz[b,F]azepine-5-propanamine 
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (13)

10-hydroxyimipramine2-hydroxyimipramine2-iodoimipramine2-nitroimipramine
Expand

Broader (6)

Adrenergic Uptake InhibitorsAminesAminoacridinesAntidepressive Agents
Expand
Affective Disorders, PsychoticAttention deficit hyperactivity disorderCYP1A2 protein, humanCYP2C19 protein, human
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Venlafaxine versus imipramine in painful polyneuropathy
Background: Tricyclic antidepressants (TCA) are often used in the treatment of painful polyneuropathy. Venlafaxine is a serotonin… 
Highly Cited
2000
Highly Cited
2000
Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial.
CONTEXT Panic disorder (PD) may be treated with drugs, psychosocial intervention, or both, but the relative and combined… 
Highly Cited
2000
Highly Cited
2000
Gender differences in treatment response to sertraline versus imipramine in chronic depression.
OBJECTIVE The authors examined gender differences in treatment response to sertraline, a selective serotonin reuptake inhibitor… 
Review
1999
Review
1999
A review of central 5-HT receptors and their function
Review
1999
Review
1999
Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action
Highly Cited
1994
Highly Cited
1994
Imipramine in patients with chest pain despite normal coronary angiograms.
BACKGROUND Ten to 30 percent of patients undergoing cardiac catheterization because of chest pain are found to have normal… 
Highly Cited
1994
Highly Cited
1994
A Comparison of Cognitive Therapy, Applied Relaxation and Imipramine in the Treatment of Panic Disorder
Recent studies have shown that cognitive therapy is an effective treatment for panic disorder. However, little is known about how… 
Highly Cited
1988
Highly Cited
1988
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus… 
Review
1967
Review
1967
The Biochemistry of Affective Disorders
  • A. Coppen
  • British Journal of Psychiatry
  • 1967
  • Corpus ID: 7203557
The title of this review would be regarded by some psychiatrists as provocative; they would relegate the biochemical concomitants… 
Review
1965
Review
1965
The catecholamine hypothesis of affective disorders: a review of supporting evidence.
  • J. Schildkraut
  • The American journal of psychiatry
  • 1965
  • Corpus ID: 38066442
The "catecholamine hypothesis of affective disorders" proposes that some, if not all, depressions are associated with an absolute… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License