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2-hydroxyimipramine

National Institutes of Health

Papers overview

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2005
2005
The hemodynamic, cardiographic, and initial pharmacokinetic characteristics of the de novo administration of the 2… Expand
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2000
2000
Abstract. Rationale: Despite the fact that carbamazepine (CBZ) is frequently added to the existing tricyclic antidepressant (TCA… Expand
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Highly Cited
1997
Highly Cited
1997
Cytochrome P450 (CYP) involved in the two major pathways of imipramine (IMI) was reappraised using human liver microsomes… Expand
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1994
1994
We studied the metabolic disposition of imipramine by measuring imipramine and its metabolites in plasma and urine simultaneously… Expand
Highly Cited
1993
Highly Cited
1993
The metabolism of imipramine by human liver microsomes was examined using a combination of five strategies. Human hepatic… Expand
Highly Cited
1991
Highly Cited
1991
The formation of three oxidative metabolites of imipramine, N‐desmethylimipramine (desipramine), 2‐hydroxyimipramine, and 10… Expand
Highly Cited
1983
Highly Cited
1983
1 Twenty-two compounds classified as antidepressants, metabolites of antidepressants or putative antidepressants were assayed for… Expand
Highly Cited
1979
Highly Cited
1979
Abstract The tricyclic antidepressant imipramine and its metabolites desipramine, 2-hydroxyimipramine and 2-hydroxydesipramine… Expand
1976
1976
The actions of ten tricyclic antidepressant drugs were evaluated with respect to inhibition of the adenylate cyclase-cyclic… Expand
Review
1966
Review
1966
  • L. Gyermek
  • International review of neurobiology
  • 1966
  • Corpus ID: 2156709
Publisher Summary This chapter describes the pharmacological characterization of the prototype agent—imipramine (I). The… Expand