2-hydroxyimipramine
National Institutes of Health
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Cytochrome P450 (CYP) involved in the two major pathways of imipramine (IMI) was reappraised using human liver microsomes…
The metabolism of imipramine by human liver microsomes was examined using a combination of five strategies. Human hepatic…
The formation of three oxidative metabolites of imipramine, N‐desmethylimipramine (desipramine), 2‐hydroxyimipramine, and 10…
1 Twenty-two compounds classified as antidepressants, metabolites of antidepressants or putative antidepressants were assayed for…