IRAK1 wt Allele

Known as: IRAK, Interleukin-1 Receptor-Associated Kinase 1 wt Allele, pelle 
Human IRAK1 wild-type allele is located within Xq28 and is approximately 9 kb in length. This allele, which encodes interleukin-1 receptor-associated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
0102019912017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll-IL-1… (More)
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Highly Cited
2002
Highly Cited
2002
Toll-like receptors (TLRs) detect microorganisms and protect multicellular organisms from infection. TLRs transduce their signals… (More)
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Highly Cited
2002
Highly Cited
2002
Toll-like receptors (TLRs), which recognize pathogen-associated molecular patterns, and members of the pro-inflammatory… (More)
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Highly Cited
2002
Highly Cited
2002
Toll/IL-1 receptor family members are central components of host defense mechanisms in a variety of species. One well conserved… (More)
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Highly Cited
2002
Highly Cited
2002
Toll-like receptor (TLR)-mediated recognition of pathogens represents one of the most important mechanisms of innate immunity and… (More)
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Highly Cited
2001
Highly Cited
2001
The recognition of microbial pathogens by the innate immune system involves Toll-like receptors (TLRs), which recognize pathogen… (More)
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Highly Cited
2000
Highly Cited
2000
Interleukin-1 (IL-1) is a proinflammatory cytokine that elicits its pleiotropic effects through activation of the transcription… (More)
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Highly Cited
1997
Highly Cited
1997
The interleukin-1 receptor (IL-1R) signaling pathway leads to nuclear factor kappa B (NF-kappaB) activation in mammals and is… (More)
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Highly Cited
1997
Highly Cited
1997
IL-1 is a proinflammatory cytokine that signals through a receptor complex of two different transmembrane chains to generate… (More)
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Highly Cited
1996
Highly Cited
1996
The pleiotropic biological activities of interleukin-1 (IL-1) are mediated by its type I receptor (IL-1RI). When the ligand binds… (More)
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