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IRAK1 gene

Known as: interleukin 1 receptor associated kinase 1, INTERLEUKIN 1 RECEPTOR-ASSOCIATED KINASE 1, pelle 
This gene plays a role in signal transduction and the immune response.
National Institutes of Health

Related topics

Related topics

7 relations
IRAK1 protein, humanIRAK1BP1 genePhosphorylationSerine/Threonine Phosphorylation

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IRAK1 wt Allele

Papers overview

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Highly Cited
2009
Highly Cited
2009
Online Supporting Material
Beer Beer Börek and pogaca 3 Börek, pogaca Brassica vegetables Cauliflower, broccoli, Brussels sprouts white cabbage… 
2007
2007
A Gain-of-Function Screen for Genes That Influence Axon Guidance Identifies the NF-κB Protein Dorsal and Reveals a Requirement for the Kinase Pelle in Drosophila Photoreceptor Axon Targeting
To identify novel regulators of nervous system development, we used the GAL4-UAS misexpression system in Drosophila to screen for… 
Review
2004
Review
2004
Life at cold seeps: a synthesis of biogeochemical and ecological data from Kazan mud volcano, eastern Mediterranean Sea
Highly Cited
2002
Highly Cited
2002
Regulation of IL-1 Receptor-Associated Kinases by Lipopolysaccharide1
IL-1R-associated kinase (IRAK) plays a pivotal role in IL-1R/Toll-like receptor (TLR)-mediated signaling and NF-κB activation… 
Highly Cited
2002
Highly Cited
2002
Molecular evolution of the NF-κB signaling system
Abstract. The mechanisms of innate immunity in vertebrates show certain overall resemblances to immune mechanisms of insects. Two… 
Highly Cited
1999
Highly Cited
1999
Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB.
Upon interleukin 1 (IL-1) stimulation, the IL-1-receptor (IL-1R)-associated kinase (IRAK) is rapidly recruited to the IL-1R… 
1999
1999
Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor.
In Drosophila, the Toll receptor signaling pathway is required for embryonic dorso-ventral patterning and at later developmental… 
Highly Cited
1998
Highly Cited
1998
Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo.
A signaling pathway initiated by activation of the transmembrane receptor Toll defines dorsoventral polarity in the Drosophila… 
Highly Cited
1997
Highly Cited
1997
An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.
A signaling pathway active on the ventral side of the Drosophila embryo defines dorsoventral polarity. A cell surface signal… 
Highly Cited
1995
Highly Cited
1995
Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.
Within the Drosophila embryo, tube and the protein kinase pelle transduce an intracellular signal generated by the transmembrane… 
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