IRAK1 gene

Known as: interleukin 1 receptor associated kinase 1, INTERLEUKIN 1 RECEPTOR-ASSOCIATED KINASE 1, pelle 
This gene plays a role in signal transduction and the immune response.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Myelodysplastic syndromes (MDSs) arise from a defective hematopoietic stem/progenitor cell. Consequently, there is an urgent need… (More)
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Highly Cited
2013
Highly Cited
2013
Upon recognition of viral components by pattern recognition receptors, such as the toll-like receptors (TLRs) and retinoic acid… (More)
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Highly Cited
2009
Highly Cited
2009
Upon recognition of viral components by pattern recognition receptors, including TLRs and retinoic acid-inducible gene I (RIG-I… (More)
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Highly Cited
2009
Highly Cited
2009
A combined forward and reverse genetic approach was undertaken to test the candidacy of IRAK1 (interleukin-1 receptor associated… (More)
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Highly Cited
2009
Highly Cited
2009
Receptor-Like Kinase (RLK)/Pelle genes play roles ranging from growth regulation to defense response, and the dramatic expansion… (More)
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Highly Cited
2008
Highly Cited
2008
Members of the IRAK family of kinases mediate Toll-like receptor (TLR) signaling. Here we show that IRAK2 was essential for… (More)
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Highly Cited
2008
Highly Cited
2008
The protein kinases IRAK [IL-1 (interleukin 1) receptor-associated kinase] 1 and 4 play key roles in a signalling pathway by… (More)
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Highly Cited
2003
Highly Cited
2003
Receptor-like kinases (RLKs) are a family of transmembrane proteins with versatile N-terminal extracellular domains and C… (More)
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Highly Cited
1997
Highly Cited
1997
The interleukin-1 receptor (IL-1R) signaling pathway leads to nuclear factor kappa B (NF-kappaB) activation in mammals and is… (More)
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Review
1996
Review
1996
The Toll-Dorsal pathway in Drosophila and the interleukin-1 receptor (IL-1R)-NF-kappa B pathway in mammals are homologous signal… (More)
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