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INSRR gene

Known as: INSULIN RECEPTOR-RELATED RECEPTOR, INSRR, Insulin Receptor-Related Receptor Gene 
This gene is thought to play a role in insulin regulation; however, the exact function is not known.
National Institutes of Health

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INSRR wt Allele
Insulin Receptor-Related Receptor, humanLigand BindingPhosphorylationReceptor Signaling

Papers overview

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2006
2006
Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary.
The insulin receptor-related receptor (IRR) is a member of the insulin receptor family that, on its own, recognizes neither… 
2005
2005
Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.
2003
2003
Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas.
PURPOSE We compared the expression of the insulin receptor-related receptor (IRR) in primary human neuroblastomas with other… 
2001
2001
Polymorphism screening of the insulin receptor-related receptor gene (INSRR) on 1q in Pima Indians.
INSRR coding for the insulin receptor-related receptor (IRR) is located within the 1q21-q23 region linked with type-2 diabetes… 
1999
1999
Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor with intrinsic tyrosine kinase activity… 
Highly Cited
1999
Highly Cited
1999
Specificity of Insulin and Insulin-like Growth Factor I Receptors Investigated using Chimeric Mini-Receptors
We have investigated the role of the C-terminal of the α-subunit in the insulin receptor family by characterizing chimeric mini… 
1999
1999
Molecular cloning and characterization of the 5′ region of the mouse trkA proto-oncogene
The trkA proto-oncogene encodes a high-affinity NGF receptor that is essential for the survival, differentiation and maintenance… 
1995
1995
Characterization of the Endogenous Insulin Receptor-related Receptor in Neuroblastomas (*)
A gene encoding a putative third member of the insulin receptor family (called the insulin receptor-related receptor or IRR) was… 
1995
1995
Activation of protein kinase C alpha inhibits signaling by members of the insulin receptor family.
Stimulation of the activity of protein kinase C by pretreatment of cells with phorbol esters was tested for its ability to… 
1995
1995
Expression of insulin receptor-related receptor rnRNA in the rat brain is highly restricted to forebrain cholinergic neurons
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