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Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia?
TLDR
In situ hybridization study revealed that fractalkine mRNA was dominantly expressed in neuronal cells particularly in the olfactory bulb, cerebral cortex, hippocampus, caudate putamen and nucleus accumbens and in glial cells throughout the whole brain. Expand
Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain
TLDR
Results suggest that MCP-1 produced in the DRG neurons is involved in the development of mechanical allodynia induced by nerve injury. Expand
Three Types of Neurochemical Projection from the Bed Nucleus of the Stria Terminalis to the Ventral Tegmental Area in Adult Mice
TLDR
The major mode of the BST–VTA projection is GABAergic, and its activation is predicted to disinhibit VTA DAergic neurons. Expand
Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats
TLDR
Results suggest that activation of distinct amygdaloid nuclei could differentially contribute to chemical somatic and visceral noxious stimuli‐induced negative affective, but not sensory components of pains. Expand
Analgesic Effects of Intrathecal Administration of P2Y Nucleotide Receptor Agonists UTP and UDP in Normal and Neuropathic Pain Model Rats
TLDR
Results suggest that the activation of UTP-sensitive P2y2 and/or P2Y4 receptors and the UDP-sensitiveP2Y6receptor, in contrast to P2X receptors, produces inhibitory effects on spinal pain transmission. Expand
Differential expression patterns of mRNAs for members of the fibroblast growth factor receptor family, FGFR‐1–FGFR‐4, in rat brain
TLDR
The present findings that theFGFR‐1, FGFR‐2, and FG FR‐3 mRNAs were expressed widely but with region‐and cell‐specificity in the brain indicate that these receptors have different roles in thebrain. Expand
Cloning and expression of a cDNA for the rat kappa-opioid receptor.
TLDR
Northern blot analysis demonstrated that kappa-opioid receptor mRNA is expressed in a regionally specific manner in rat brain. Expand
Molecular biology of the opioid receptors: structures, functions and distributions
TLDR
The molecular cloning of the opioid receptor gene family is described and studies of the structure-function relationships, modes of coupling to second messenger systems, pharmacological effects of antisense oligonucleotide and anatomical distributions of opioid receptors are described. Expand
Mu opioid receptor-dependent and independent components in effects of tramadol
TLDR
The results strongly support the idea suggested in the previous pharmacological studies that MOP and the adrenaline alpha2 receptor mediate most of the analgesic properties of tramadol. Expand
Double in situ hybridization study on coexistence of mu-, delta- and kappa-opioid receptor mRNAs with preprotachykinin A mRNA in the rat dorsal root ganglia.
TLDR
The results suggest that mu- and kappa-OPRs exist on most of and a part of the primary afferent terminals containing SP, respectively, and suggest the possibility that OPRs co-exist with other neurotransmitters and/or neuromodulators than SP in thePrimary afferent neurons. Expand
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