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IL9 protein, human

Known as: Interleukin 9 Precursor, Homolog of Mouse T Cell and Mast Cell Growth Factor 40, HP40 
Interleukin-9 (144 aa, ~16 kDa) is encoded by the human IL9 gene. This protein plays a role in the growth of helper T-cells.
National Institutes of Health

Related topics

Related topics

15 relations
Cell ProliferationCell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor Binding

Broader (1)

Interleukin-9

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells.
IL-12 p40-related cytokines such as IL-12 p35/p40 heterodimer and IL-23 (p19/p40) are potent regulators of adaptive immune… 
Highly Cited
2003
Highly Cited
2003
c-Jun N-Terminal Kinase Negatively Regulates Lipopolysaccharide-Induced IL-12 Production in Human Macrophages: Role of Mitogen-Activated Protein Kinase in Glutathione Redox Regulation of IL-12…
Although c-Jun N-terminal kinase (JNK) plays an important role in cytokine expression, its function in IL-12 production is… 
Highly Cited
2002
Highly Cited
2002
In Vivo Clearance of an Intracellular Bacterium, Francisella tularensis LVS, Is Dependent on the p40 Subunit of Interleukin-12 (IL-12) but Not on IL-12 p70
ABSTRACT To determine the role of interleukin-12 (IL-12) in primary and secondary immunity to a model intracellular bacterium, we… 
Highly Cited
1999
Highly Cited
1999
Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells.
We investigated whether human monocyte-derived dendritic cells (DCs) differed from tonsillar B cells in the set of cell fate… 
Highly Cited
1997
Highly Cited
1997
In vivo production and function of IL-12 p40 homodimers.
The bioactivity of IL-12 is mediated by heterodimers of disulfide-linked p35 and p40 protein subunits. Homodimeric p40 competes… 
Highly Cited
1997
Highly Cited
1997
Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia.
We examined whether the cytokine IL-12 could be induced locally in the brain or in glial cell cultures following LPS treatment… 
Highly Cited
1996
Highly Cited
1996
Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit.
IL-12 enhances IFN-gamma production by NK cells and T lymphocytes and plays a pivotal role in the development of Th1 cells… 
Highly Cited
1993
Highly Cited
1993
An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae.
The p34CDC28 protein from Saccharomyces cerevisiae is a homolog of the p34cdc2 protein kinase, a fundamental regulator of cell… 
Highly Cited
1990
Highly Cited
1990
Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene.
P40 is a cytokine that was originally identified in the mouse as a T cell growth factor, but whose spectrum of potential targets… 
Highly Cited
1989
Highly Cited
1989
Mapping early somatosensory evoked potentials in selective attention: critical evaluation of control conditions used for titrating by difference the cognitive P30, P40, P100 and N140.
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