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IL9 protein, human

Known as: Interleukin 9 Precursor, Homolog of Mouse T Cell and Mast Cell Growth Factor 40, HP40 
Interleukin-9 (144 aa, ~16 kDa) is encoded by the human IL9 gene. This protein plays a role in the growth of helper T-cells.
National Institutes of Health

Related topics

Related topics

15 relations
Cell ProliferationCell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor Binding

Broader (1)

Interleukin-9

Papers overview

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Highly Cited
2003
Highly Cited
2003
c-Jun N-Terminal Kinase Negatively Regulates Lipopolysaccharide-Induced IL-12 Production in Human Macrophages: Role of Mitogen-Activated Protein Kinase in Glutathione Redox Regulation of IL-12…
Although c-Jun N-terminal kinase (JNK) plays an important role in cytokine expression, its function in IL-12 production is… 
2002
2002
Profiles of IFN‐γ and its regulatory cytokines (IL‐12, IL‐18 and IL‐10) in peripheral blood mononuclear cells from patients with multidrug‐resistant tuberculosis
This study investigated the profiles of IFN‐γ and its regulatory cytokines (IL‐12, IL‐18 and IL‐10) in response to a purified… 
2001
2001
Suppression of Il-12 transcription in macrophages following Fc gamma receptor ligation.
Ligating Fc gamma R on macrophages results in suppression of IL-12 production. We show that Fc gamma R ligation selectively down… 
Highly Cited
1998
Highly Cited
1998
Synergistic Regulation of the Human Interleukin-12 p40 Promoter by NFκB and Ets Transcription Factors in Epstein-Barr Virus-transformed B Cells and Macrophages*
Monocytes/macrophages produce interleukin-12 (IL-12) in response to pathogenic stimulation, whereas most Epstein-Barr virus… 
Highly Cited
1998
Highly Cited
1998
Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.
A major goal of tumor immunotherapy is the effective eradication of established metastases associated with the induction of a T… 
Highly Cited
1997
Highly Cited
1997
In vivo production and function of IL-12 p40 homodimers.
The bioactivity of IL-12 is mediated by heterodimers of disulfide-linked p35 and p40 protein subunits. Homodimeric p40 competes… 
Highly Cited
1996
Highly Cited
1996
Brucella abortus as a potential vaccine candidate: induction of interleukin-12 secretion and enhanced B7.1 and B7.2 and intercellular adhesion molecule 1 surface expression in elutriated human…
Development of a vaccine which is capable of generating a strong cellular immune response associated with gamma interferon (IFN… 
1994
1994
Development of a microsatellite genetic map spanning 5q31–q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9
1991
1991
Influence of stimulus repetition rate on cortical somatosensory potentials evoked by median nerve stimulation: Implications for generation mechanisms
Highly Cited
1990
Highly Cited
1990
Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene.
P40 is a cytokine that was originally identified in the mouse as a T cell growth factor, but whose spectrum of potential targets… 
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