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Global Challenge of Multidrug-Resistant Acinetobacter baumannii
TLDR
This review summarizes the worldwide emergence of antibiotic-resistant A. baumannii as a nosocomial pathogen and focuses on its mechanisms of resistance against selected antibiotics. Expand
Comparative Genome Sequence Analysis of Multidrug-Resistant Acinetobacter baumannii
TLDR
Four hundred seventy-five genes are shared among all six clinical isolates but absent from the related environmental species Acinetobacter baylyi ADP1 and suggest physiological features of A. baumannii that are related to adaptation for growth in association with humans. Expand
Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients.
BACKGROUND Colonization and infection with vancomycin-resistant enterococci have been associated with exposure to antibiotics that are active against anaerobes. In mice that have intestinalExpand
What's new in antibiotic resistance? Focus on beta-lactamases.
TLDR
It is distressing that carbapenemases (serine and metallo-beta-lactamases) are being found in many of the same bacteria that harbor ESBLs, for example Klebsiella pneumoniae. Expand
Analysis of Antibiotic Resistance Genes in Multidrug-Resistant Acinetobacter sp. Isolates from Military and Civilian Patients Treated at the Walter Reed Army Medical Center
TLDR
A “snapshot” of the complex genetic background responsible for antimicrobial resistance in Acinetobacter spp. Expand
Identification of a New Allelic Variant of the Acinetobacter baumannii Cephalosporinase, ADC-7 β-Lactamase: Defining a Unique Family of Class C Enzymes
TLDR
The coalescence of Acinetobacter ampC β-lactamases into a single common ancestor and the substantial phylogenetic distance separating them from other ampC genes support the logical value of developing a system of nomenclature for these AcinetOBacter cephalosporinase genes. Expand
Extended-Spectrum β-Lactamases in Klebsiella pneumoniae Bloodstream Isolates from Seven Countries: Dominance and Widespread Prevalence of SHV- and CTX-M-Type β-Lactamases
TLDR
The widespread emergence and proliferation of CTX-M-type ESBLs is particularly noteworthy and may have important implications for clinical microbiology laboratories and for physicians treating patients with serious K. pneumoniae infections. Expand
Occurrence, Distribution, and Origins of Streptococcus pneumoniae Serotype 6C, a Recently Recognized Serotype
TLDR
Serotype 6C warrants consideration for addition to future conjugate pneumococcal vaccines, and its occurrence, nationwide distribution, diversity, likely origins, and increasing incidence after 2001 are documents. Expand
Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA.
TLDR
The complex beta-lactamase background of KPC-Kp isolates that are emerging in multiple centres in the Eastern USA demonstrated the prevalence of a single dominant clone suggests that interstate transmission has occurred. Expand
Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type beta-lactamases.
TLDR
The widespread emergence and proliferation of CTX-M-type ESBLs is particularly noteworthy and may have important implications for clinical microbiology laboratories and for physicians treating patients with serious K. pneumoniae infections. Expand
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