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Interleukin-9

Known as: Interleukin 9, IL-9, T Cell Growth Factor P40 
A multifunctional cytokine secreted by primarily by activated TH2 CELLS that may play a role as a regulator of allergic INFLAMMATION. It has been… Expand
National Institutes of Health

Related topics

Related topics

15 relations
IL9 geneIn BloodProcess of secretionRecombinant Interleukin-9
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Narrower (1)

IL9 protein, human

Broader (1)

cytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy.
Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin-9 (IL-9). However, the primary… Expand
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Highly Cited
2013
Highly Cited
2013
Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP.
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine important for the initiation and development of T… Expand
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Highly Cited
2012
Highly Cited
2012
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells.
Interleukin 9 (IL-9) is a pleiotropic cytokine that can regulate autoimmune responses by enhancing regulatory CD4(+)FoxP3(+) T… Expand
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Highly Cited
2011
Highly Cited
2011
Interleukin 9 fate reporter reveals induction of innate IL-9 response in lung inflammation
Interleukin 9 (IL-9) is a cytokine linked to lung inflammation, but its cellular origin and function remain unclear. Here we… Expand
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Highly Cited
2010
Highly Cited
2010
The transcription factor PU.1 is required for the development of interleukin 9-producing T cells and allergic inflammation
CD4+ helper T cells acquire effector phenotypes that promote specialized inflammatory responses. We show that the ETS-family… Expand
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Highly Cited
2009
Highly Cited
2009
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
The development of T helper (TH)17 and regulatory T (Treg) cells is reciprocally regulated by cytokines. Transforming growth… Expand
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Highly Cited
2006
Highly Cited
2006
Mast cells are essential intermediaries in regulatory T-cell tolerance
Contrary to the proinflammatory role of mast cells in allergic disorders, the results obtained in this study establish that mast… Expand
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Highly Cited
2002
Highly Cited
2002
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
Signals generated by T cell receptor (TCR) and CD28 engagement are required for optimal T cell activation, but how these signals… Expand
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Highly Cited
2001
Highly Cited
2001
Interleukin 9 promotes influx and local maturation of eosinophils.
The interleukin 9 (IL-9) pathway has recently been associated with the asthmatic phenotype including an eosinophilic tissue… Expand
Highly Cited
1992
Highly Cited
1992
Expression cloning of the murine and human interleukin 9 receptor cDNAs.
Interleukin 9 (IL-9) is a T-cell-derived lymphokine that induces the proliferation of various lymphoid and hemopoietic cells. A… Expand
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