IL28B protein, human

Known as: Interleukin-28C, Interferon Lambda 3, IL-28B protein, human 
Interferon lambda-3 (196 aa, ~22 kDa) is encoded by the human IFNL3 gene. This protein plays a role in cytokine signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
0102020092017

Papers overview

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2014
2014
IFNL3, which encodes interferon-λ3 (IFN-λ3), has received considerable attention in the hepatitis C virus (HCV) field, as many… (More)
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2014
2014
BACKGROUND & AIMS Single nucleotide polymorphisms (SNPs) near the interferon lambda 3 (IFNL3, previously known as IL28B) region… (More)
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Highly Cited
2013
Highly Cited
2013
Chronic infection with hepatitis C virus (HCV) is a common cause of liver cirrhosis and cancer. We performed RNA sequencing in… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Chronic hepatitis C virus is difficult to treat and affects approximately 3 million Americans. Protease inhibitors… (More)
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2012
2012
BACKGROUND & AIMS A substantial proportion of hepatitis C virus genotype 1 (HCV-1) patients achieved a sustained virological… (More)
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2011
2011
We focused on determining the most accurate and convenient genotyping methods and most appropriate single nucleotide polymorphism… (More)
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2011
2011
UNLABELLED The identification of associations between interleukin-28B (IL-28B) variants and the spontaneous clearance of… (More)
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Highly Cited
2011
Highly Cited
2011
UNLABELLED Polymorphism in the interleukin-28B (IL28B) gene region, encoding interferon (IFN)-λ3, is strongly predictive of… (More)
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Highly Cited
2010
Highly Cited
2010
UNLABELLED Genetic host factors may modify the course of the hepatitis C virus (HCV) infection. Very recently, a genome-wide scan… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS We recently identified a polymorphism upstream of interleukin (IL)-28B to be associated with a 2-fold… (More)
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