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Interleukins

Known as: IL, Interleukins [Chemical/Ingredient], unspecified interleukin 
Interleukin is the generic name for a group of well-characterized cytokines that are produced by leukocytes and other cell types. They have a broad… 
National Institutes of Health

Related topics

Related topics

49 relations
AntigensBiological MarkersCell Proliferation Regulatory ProcessCytokine Gene
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Narrower (23)

D17Wsu104e protein, mouseIFNL4 protein, humanIL-38 protein, humanIL19 protein, human
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Broader (4)

Growth FactorGrowth SubstancesLymphokinescytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
A Meta-Analysis of Cytokines in Major Depression
Review
2009
Review
2009
Immunological and inflammatory functions of the interleukin-1 family.
  • C. Dinarello
  • Annual review of immunology
  • 2009
  • Corpus ID: 25017800
More than any other cytokine family, the interleukin (IL)-1 family is closely linked to the innate immune response. This linkage… 
Highly Cited
2006
Highly Cited
2006
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
On activation, T cells undergo distinct developmental pathways, attaining specialized properties and effector functions. T-helper… 
Highly Cited
2005
Highly Cited
2005
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
CD4+ T cells producing interleukin 17 (IL-17) are associated with autoimmunity, although the precise mechanisms that control… 
Highly Cited
2005
Highly Cited
2005
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Interleukin 17 (IL-17) has been linked to autoimmune diseases, although its regulation and function have remained unclear. Here… 
Highly Cited
2003
Highly Cited
2003
Increased expression of interleukin 17 in inflammatory bowel disease
Background and aim: Interleukin (IL) 17 is a cytokine which exerts strong proinflammatory activities. In this study we evaluated… 
Review
1997
Review
1997
Gp130 and the interleukin-6 family of cytokines.
Receptors for most interleukins and cytokines that regulate immune and hematopoietic systems belong to the class I cytokine… 
Highly Cited
1996
Highly Cited
1996
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
Bacterial infection stimulates the host to mount a rapid inflammatory response. A 6-base DNA motif consisting of an unmethylated… 
Highly Cited
1994
Highly Cited
1994
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis…
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines… 
Highly Cited
1991
Highly Cited
1991
Macrophage deactivation by interleukin 10
Recombinant mouse interleukin 10 (IL-10) was exceedingly potent at suppressing the ability of mouse peritoneal macrophages (m phi… 
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