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Side population purified from hepatocellular carcinoma cells harbors cancer stem cell–like properties
Recent advances in stem cell biology enable us to identify cancer stem cells in solid tumors as well as putative stem cells in normal solid organs. In this study, we applied side population (SP) cellExpand
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Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic Patients with Chronic Hepatitis C in Japan
Hepatitis C virus (HCV) infection rarely resolves spontaneously once it becomes chronic (1). Most patients remain asymptomatic for a long period, with liver cirrhosis developing after approximatelyExpand
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Histologic Improvement of Fibrosis in Patients with Hepatitis C Who Have Sustained Response to Interferon Therapy
Chronic hepatitis C is a common disease that may progress to cirrhosis (1-4) and hepatocellular carcinoma (5-8). In some patients, treatment with interferon, alone or in combination with ribavirin,Expand
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Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease
To investigate the hepatitis B virus (HBV) genotype‐related differences in the progression of liver disease, 585 patients with chronic HBV infection including 258 with histologically verified chronicExpand
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Intraductal Papillary Neoplasms of the Bile Duct
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart ofExpand
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Antiviral Therapy for Cirrhotic Hepatitis C: Association with Reduced Hepatocellular Carcinoma Development and Improved Survival
Context Few studies address long-term outcomes of antiviral therapy for patients with chronic hepatitis C and cirrhosis. Contribution This prospective study of adults with chronic hepatitis C andExpand
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Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014
The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published in 2009. DueExpand
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Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label,
BACKGROUND Compared with other countries, patients with chronic hepatitis C infection in Japan tend to be older, have more advanced liver disease, and are more likely to have been previously treatedExpand
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APASL consensus statements and management algorithms for hepatitis C virus infection
The Asian Pacific Association for the Study of the Liver (APASL) convened an international working party on the “APASL Consensus Statements and Management Algorithms for Hepatitis C Virus Infection”Expand
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