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IL1RAPL1 gene

Known as: INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN-LIKE 1, interleukin 1 receptor accessory protein like 1, INTERLEUKIN 1 RECEPTOR 8 
This gene is involved in signal transduction.
National Institutes of Health

Related topics

Related topics

6 relations
Cytokine Signaling ProcessIntercellular Communication ProcessLigand BindingReceptor Signaling

Broader (1)

IL1RAPL1 protein, human

Narrower (1)

IL1RAPL1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
OBJECTIVES The IL-1 family member IL-37 was recently characterized as a fundamental inhibitor of innate inflammation. We… 
2014
2014
IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours
IL-1 receptor accessory protein-like 1 (IL1RAPL1) is responsible for nonsyndromic intellectual disability and is associated with… 
Highly Cited
2012
Highly Cited
2012
Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151
Genistein has been shown to suppress the growth of several cancers through modulation of various pathways. However, the effects… 
Review
2012
Review
2012
β-Thalassemia trait association with autoimmune diseases: β-globin locus proximity to the immunity genes or role of hemorphins?
Thalassemia major continues to be a significant health problem for Mediterranean, Afro-Arabic countries, India and South Easth… 
2011
2011
Deletion of the immunoglobulin domain of IL1RAPL1 results in nonsyndromic X‐linked intellectual disability associated with behavioral problems and mild dysmorphism
X‐Linked intellectual disability accounts for a significant fraction of males with cognitive impairment. Many of these males… 
Review
2011
Review
2011
Intragenic deletions of IL1RAPL1: Report of two cases and review of the literature
IL1RAPL1 (interleukin‐1 receptor accessory protein‐like 1) located at Xp21.3‐22.1 has repeatedly been shown to be deleted in… 
2010
2010
Neuronal JNK pathway activation by IL-1 is mediated through IL1RAPL1, a protein required for development of cognitive functions
Interleukin-1-Receptor Accessory Protein Like 1 (IL1RAPL1) gene mutations are associated to cognitive impairment ranging from non… 
Highly Cited
2006
Highly Cited
2006
A truncating mutation in the IL1RAPL1 gene is responsible for X‐linked mental retardation in the MRX21 family
X‐linked mental retardation (XLMR) is a genetically heterogeneous condition, due to mutations in at least 50 genes, involved in… 
2003
2003
A complex deletion-inversion-deletion event results in a chimeric IL1RAPL1-dystrophin transcript and a contiguous gene deletion syndrome
We originally identified the IL1RAPL1 gene through its partial deletion in a patient with Becker muscular dystrophy (BMD… 
Highly Cited
2000
Highly Cited
2000
Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1–Xp21.3 mental retardation
X-linked mental retardation is estimated to affect approximately 1 in 600 males. Although numerous genes responsible for… 
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