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The function of brown adipose tissue is to transfer energy from food into heat; physiologically, both the heat produced and the… Expand Ghrelin is an acylated peptide that stimulates the release of growth hormone from the pituitary. Ghrelin-producing neurons are… Expand New information regarding neuronal circuits that control food intake and their hormonal regulation has extended our understanding… Expand The discovery of the peptide hormone ghrelin, an endogenous ligand for the growth hormone secretagogue (GHS) receptor, yielded… Expand It is now nearly 5 years since the last of the currently recognised 5-HT receptors was identified in terms of its cDNA sequence… Expand The hypothalamus plays a central role in the integrated control of feeding and energy homeostasis. We have identified two novel… Expand We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share… Expand The ob gene product, leptin, is an important circulating signal for the regulation of body weight. To identify high affinity… Expand A peptide has been isolated from ovine hypothalamus which, at 1 x 10-9M, inhibits secretion in vitro of immunoreactive rat or… Expand 1. Stimulation of the reticular formation of the brain stem evokes changes in the EEG, consisting of abolition of synchronized… Expand