Hyperimmunoglobulin M syndrome

Known as: Immunodeficiency Syndromes, Hyper-IgM, Hyper-IgM Syndrome, Immunodeficiency with Hyper IgM Syndrome 
A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G… (More)
National Institutes of Health

Related topics

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13 relations
CD40LG geneCD40LG wt AlleleHyper-IgM Immunodeficiency Syndrome, Type 1In Blood
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Narrower (4)

Hyper-IgM Immunodeficiency Syndrome, Type 2Hyper-IgM Immunodeficiency Syndrome, Type 3Hyper-IgM Immunodeficiency Syndrome, Type 5IMMUNODEFICIENCY WITH HYPER-IgM, TYPE 4

Papers overview

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Highly Cited
2011
Highly Cited
2011
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
Patients with asthma, a major public health problem, are at high risk for serious disease from influenza virus infection, but the… (More)
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Review
2010
Review
2010
The many paths to asthma: phenotype shaped by innate and adaptive immunity
Asthma is a very complex and heterogeneous disease that is characterized by airway inflammation and airway hyper-reactivity (AHR… (More)
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Review
2009
Review
2009
Obesity and asthma.
Population-based studies have defined a significant, bidirectional, dose-dependent association between obesity and asthma… (More)
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Highly Cited
2006
Highly Cited
2006
Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia.
BACKGROUND Adult Burkitt-type lymphoma (BL) and acute lymphoblastic leukemia (B-ALL) are rare entities composing 1% to 5% of non… (More)
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Highly Cited
2005
Highly Cited
2005
High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine…
PURPOSE To determine the response, failure-free survival (FFS), and overall survival rates and toxicity of rituximab plus an… (More)
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Highly Cited
2004
Highly Cited
2004
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
Exaggerated levels of VEGF (vascular endothelial growth factor) are present in persons with asthma, but the role(s) of VEGF in… (More)
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Highly Cited
2004
Highly Cited
2004
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.
Imatinib mesylate, an inhibitor of the Bcr-Abl tyrosine kinase, has modest activity in refractory/relapsed Philadelphia… (More)
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Highly Cited
2004
Highly Cited
2004
Long-term follow-up results of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper-CVAD), a dose-intensive regimen, in adult acute lymphocytic leukemia.
BACKGROUND Modern intensive chemotherapy regimens have improved the prognosis for patients with adult acute lymphocytic leukemia… (More)
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Highly Cited
2000
Highly Cited
2000
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
BACKGROUND Interleukin-5 (IL-5) is essential for the formation of eosinophils, which are thought to have a major role in the… (More)
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Highly Cited
2000
Highly Cited
2000
Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia.
PURPOSE To evaluate the efficacy and toxicity of Hyper-CVAD (fractionated cyclophosphamide, vincristine, doxorubicin, and… (More)
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