J. Polak

Publications1,313
h-index129
Citations64,566
Highly Influential Citations1,265
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Human distribution and release of a putative new gut hormone, peptide YY.
A radioimmunoassay has been developed for the new intestinal hormonal peptide tyrosine tyrosine [peptide YY (PYY)]. Peptide YY concentrations were measured in separated layers of the human… Expand
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  • 44
Third-Generation Biomedical Materials
Whereas second-generation biomaterials were designed to be either resorbable or bioactive, the next generation of biomaterials is combining these two properties, with the aim of developing materials… Expand
  • 2,106
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The immunolocalization of protein gene product 9.5 using rabbit polyclonal and mouse monoclonal antibodies.
In order to assess the potential of protein gene product (PGP) 9.5 as a marker of the nervous and neuroendocrine systems, we examined its immunolocation in human, rat and guinea-pig tissues, using a… Expand
  • 298
  • 24
Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus
Immunohistochemical methods were used in the rat to plot the distribution of neuropeptide Y (NPY) immunoreactivity in the paraventricular (PVH) and supraoptic (SO) nuclei of the hypothalamus, and a… Expand
  • 655
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Neuropeptide Y distribution in the rat brain.
A massive neuronal system was detected by immunocytochemistry and radioimmunoassay with antibodies to neuropeptide Y, the recently isolated peptide of the pancreatic polypeptide family.… Expand
  • 1,076
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Expression of angiogenesis‐related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis
Pulmonary arteries of patients with severe pulmonary hypertension (SPH) presenting in an idiopathic form (primary PH‐PPH) or associated with congenital heart malformations or collagen vascular… Expand
  • 452
  • 20
Abdominal Aortic Calcific Deposits Are an Important Predictor of Vascular Morbidity and Mortality
BackgroundThe impact of abdominal arterial calcific deposits on the prediction of cardiovascular disease (CVD) over a long follow-up interval deserves greater scrutiny. Methods and ResultsLateral… Expand
  • 517
  • 18
Localization of nitric oxide synthase in the adult rat brain.
The distribution of the immunoreactivity to nitric oxide synthase has been examined from rostral to caudal areas of the rat central nervous system using light microscopy. Endogenous nitric oxide… Expand
  • 368
  • 15
Differentiation of osteoblasts and in vitro bone formation from murine embryonic stem cells.
Pluripotent embryonic stem (ES) cells have the potential to differentiate to all fetal and adult cell types and might represent a useful cell source for tissue engineering and repair. Here we show… Expand
  • 405
  • 15
Spectroscopic study of human lung epithelial cells (A549) in culture: living cells versus dead cells.
The noninvasive analysis of living cells grown on 3-dimensional scaffold materials is a key point in tissue engineering. In this work we show the capability of Raman spectroscopy for use as a… Expand
  • 276
  • 15