Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Hyper-IgM Immunodeficiency Syndrome, Type 3

Known as: Hyper-IgM Immunodeficiency Syndrome Type 3, HIGM3 Syndrome, Hyper IgM Syndrome 3 
Hyper-IgM immunodeficiency subtype resulting from mutation in the gene encoding CD40 ANTIGEN.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Hyper-IgM syndrome due to CD40 deficiency (HIGM3) is a rare disease with only a few reported cases of haematopoietic stem cell… Expand
Is this relevant?
Review
2013
Review
2013
PurposeHyper-IgM syndrome due to CD40 deficiency (HIGM3) is a rare form of primary immunodeficiency with few reported cases. In… Expand
  • figure 1
  • table III
  • figure 2
  • figure 3
Is this relevant?
2012
2012
Mutations of the CD40 gene have been found in patients with autosomal recessive hyper‐immunoglobulin M (HIGM) syndrome type 3… Expand
Is this relevant?
2010
2010
The hyper-IgM syndromes (HIGMs) are immunodeficiencies that have taught us much about the details of humoral immunity. In this… Expand
Is this relevant?
2010
2010
The hyper-IgM syndromes (HIGMs) are immunodeficiencies that have taught us much about the details of humoral immunity. In this… Expand
Is this relevant?
Review
2005
Review
2005
Antibody deficiency diseases are common collectively. The clinical presentation of these disorders is extremely variable and they… Expand
  • table I
  • table II
  • figure 1
  • table IV
  • figure 2
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Hyper-IgM syndrome (HIGM) is a heterogeneous condition characterized by impaired Ig class-switch recombination (CSR). The… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
We have recently identified 2 patients with a rare autosomal recessive form of hyper IgM disease, known as HIGM3, caused by… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2003
2003
BACKGROUND Inducible CO-stimulatory molecule (ICOS), the third member of the CD28/CTLA4 family, is expressed by activated T cells… Expand
Is this relevant?