Hyper-IgM Immunodeficiency Syndrome, Type 2

Known as: Hyper-IgM Immunodeficiency Syndrome Type 2, HIGM2 Syndrome, Hyper IgM Syndrome 2 
An autosomal recessive immunodeficiency that is caused by mutation(s) in the AICDA gene, single-stranded DNA cytosine deaminase. It is characterized… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Macrolides, such as clarithromycin and azithromycin, possess antimicrobial, immunomodulatory, and potential antiviral properties… (More)
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2011
2011
BACKGROUND An important use of data obtained from microarray measurements is the classification of tumor types with respect to… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Reduced lung function is a feature of chronic asthma, which becomes apparent at school age. Unknown factors between… (More)
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2006
2006
Interleukin-1 (IL-1) is a proinflammatory cytokine and IL-1 receptor antagonist (IL-1ra) is a natural inhibitor that binds to IL… (More)
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2005
2005
Asthma-like symptoms and airway hyper-responsiveness (AHR) are frequently reported in children subsequent to premature birth and… (More)
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2005
2005
BACKGROUND IL-4 is a key factor for T helper type 2 (Th2) differentiation and Ig class switching to IgE and IgG(4) during the… (More)
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Highly Cited
2003
Highly Cited
2003
Hyper-IgM syndrome (HIGM) is a heterogeneous condition characterized by impaired Ig class-switch recombination (CSR). The… (More)
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Highly Cited
2000
Highly Cited
2000
The activation-induced cytidine deaminase (AID) gene, specifically expressed in germinal center B cells in mice, is a member of… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Previous studies have not resolved the importance of several potential risk factors for the development of childhood… (More)
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Review
1992
Review
1992
Immunodeficiency with hyper-IgM (HIM) is a rare disorder characterized by recurrent infections associated with low IgG and IgA… (More)
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