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CD40LG gene

Known as: T-B cell-activating molecule, CD40 ANTIGEN LIGAND, hyper-IgM syndrome 
This gene plays a role in the stimulation of B cells in immune responses.
National Institutes of Health

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B-Cell ActivationCD40 LigandCD40 Ligand, humanCell Death

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CD40LG wt Allele

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Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A Novel CD40L Mutation Associated with X-Linked Hyper IgM Syndrome in a Chinese Family
ABSTRACT Background: Mutations in CD40 ligand gene (CD40L) affecting immunoglobulin class-switch recombination and somatic… 
2019
2019
Meta-Analysis of HTLV-1-Infected Patients Identifies CD40LG and GBP2 as Markers of ATLL and HAM/TSP Clinical Status: Two Genes Beat as One
Human T-lymphotropic virus 1 (HTLV-1) was the first recognized human retrovirus. Infection can lead to two main symptomatologies… 
2018
2018
Clinical and molecular features of X-linked hyper IgM syndrome - An experience from North India.
2017
2017
Indoleamine 2,3-dioxygenase and inducible nitric oxide synthase mediate immune tolerance induced by CTLA4Ig and anti-CD154 hematopoietic stem cell transplantation in a sensitized mouse model
Cytotoxic T-lymphocyte-associated protein 4 immunoglobulin (CTLA4Ig) and anti-cluster of differentiation 154 (anti-CD154) are… 
2014
2014
44-plex cytokine profile of cholesteatoma
Abstract Conclusion: A nuanced profiling was achieved by the simultaneous analysis of 44 cytokines in cholesteatoma. The novel… 
2014
2014
Correlation of glucocorticoid-mediated E4BP4 upregulation with altered expression of pro- and anti-apoptotic genes in CEM human lymphoblastic leukemia cells.
2008
2008
Reactivation of inactive X chromosome: a potential culprit and therapeutic target for systemic lupus erythematosus.
2006
2006
[Changes in gene expression in the course of proliferative processes in the parathyroid gland].
The aim of this study was to investigate the changes in expression pattern of the most important genes connected with apoptosis… 
1996
1996
Classification of mutations in the human CD40 ligand, gp39, that are associated with X‐linked hyper IgM syndrome
The interaction between the T cell activation antigen gp39 and CD40, its receptor CD40 on B cells, plays a critical role in the… 
Highly Cited
1995
Highly Cited
1995
Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesis.
The interaction between gp39 (CD40L, TRAP, T-BAM) on activated T cells and mast cells and CD40 on antigen-presenting cells… 
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