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CD40LG gene

Known as: T-B cell-activating molecule, CD40 ANTIGEN LIGAND, hyper-IgM syndrome 
This gene plays a role in the stimulation of B cells in immune responses.
National Institutes of Health

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B-Cell ActivationCD40 LigandCD40 Ligand, humanCell Death

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CD40LG wt Allele

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Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
X-linked hyper-IgM syndrome complicated with interstitial pneumonia and liver injury: a new mutation locus in the CD40LG gene
X-linked hyper-IgM syndrome (HIGM1) is a rare primary immunodeficiency syndrome caused by mutations in the CD40L gene. The major… 
2015
2015
Polymorphism of X-linked CD40 ligand gene associated with pulmonary tuberculosis in the Han Chinese population
Among those developing tuberculosis (TB) after exposure to Mycobacterium tuberculosis, approximately 70% are males. Host genetic… 
2014
2014
44-plex cytokine profile of cholesteatoma
Abstract Conclusion: A nuanced profiling was achieved by the simultaneous analysis of 44 cytokines in cholesteatoma. The novel… 
2014
2014
CD137 Expression Identifies Leukemia Specific CTL after in Vitro Priming of Cord Blood T Cells Previously Expanded By CD3/CD28 Co-Stimulation
2011
2011
CD40-ligand/interleukin-2 vaccines in chronic lymphocytic leukemia: the impact of vaccine design.
Chronic lymphocytic leukemia (CLL) appears to be very susceptible to the allogeneic T cells that mediate the graft-versus… 
2010
2010
Expression profiling of immune-associated genes in peripheral blood mononuclear cells reveals baseline differences in co-stimulatory signalling between nonagenarians and younger controls: the…
The human immune system, especially the adaptive branch, substantially declines with ageing. Several distinct immunosenescent… 
2008
2008
Reactivation of inactive X chromosome: a potential culprit and therapeutic target for systemic lupus erythematosus.
2006
2006
[Changes in gene expression in the course of proliferative processes in the parathyroid gland].
The aim of this study was to investigate the changes in expression pattern of the most important genes connected with apoptosis… 
2005
2005
[Construction of the recombinant adenovirus vector expressing human CD40 ligand gene].
OBJECTIVE To construct a recombinant adenovirus vector expressing hCD40L gene and explore it in the use of anti-tumor gene… 
Highly Cited
1995
Highly Cited
1995
Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesis.
The interaction between gp39 (CD40L, TRAP, T-BAM) on activated T cells and mast cells and CD40 on antigen-presenting cells… 
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