CD40 Ligand

Known as: TRAP ligand, T-Cell gp39 Antigen, T-cell antigen gp39 
A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces… (More)
National Institutes of Health

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Highly Cited
1998
Highly Cited
1998
CD40 ligand (CD40L, CD154), a transmembrane protein structurally related to the cytokine TNF-α, was originally identified on… (More)
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Highly Cited
1998
Highly Cited
1998
Although in vivo priming of CD8+ cytotoxic T lymphocytes (CTLs) generally requires the participation of CD4+ T-helper lymphocytes… (More)
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Highly Cited
1998
Highly Cited
1998
Increasing amounts of evidence support the involvement of inflammation and immunity in atherogenesis but mediators of… (More)
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Highly Cited
1997
Highly Cited
1997
Increasing evidence supports involvement of inflammation and immunity in atherogenesis. We report here that CD40 ligand (CD40L… (More)
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Highly Cited
1997
Highly Cited
1997
Selective inhibition of T cell costimulation using the B7-specific fusion protein CTLA4-Ig has been shown to induce long-term… (More)
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Highly Cited
1996
Highly Cited
1996
We investigated the possibility that T helper cells might enhance the stimulatory function of dendritic cells (DCs). We found… (More)
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Highly Cited
1994
Highly Cited
1994
Dendritic cells, the professional antigen-presenting cells (APC) involved in T cell priming, express CD40, a molecule which… (More)
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Highly Cited
1994
Highly Cited
1994
To study the potential roles of CD40L in immune responses, we generated CD40L-deficient mice by gene targeting. Similar to the… (More)
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Highly Cited
1994
Highly Cited
1994
An engagement of CD40 with CD40 ligand (CD40L) expressed on activated T cells is known to provide an essential costimulatory… (More)
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Highly Cited
1994
Highly Cited
1994
Individuals with X-linked hyper-IgM syndrome fail to express functional CD40 ligand (CD40L) and, as a consequence, are incapable… (More)
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