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CD40 Antigens

Known as: TNFRSF5 Receptor, Antigens, CD40 [Chemical/Ingredient], CDw40 Antigen 
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL… Expand
National Institutes of Health

Related topics

Related topics

41 relations
ApoptosisApoptosis Regulatory ProteinsB-Cell ActivationB-Lymphocytes
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Broader (1)

CD Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo.
Bone homeostasis is regulated by a delicate balance between osteoblastic bone formation and osteoclastic bone resorption… Expand
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Highly Cited
2006
Highly Cited
2006
Inhibitory effects of B cells on antitumor immunity.
B-cell functions in antitumor immunity are not well understood. In this study, we evaluated the role of B cells in the… Expand
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Highly Cited
2003
Highly Cited
2003
Elevated Plasma Levels of the Atherogenic Mediator Soluble CD40 Ligand in Diabetic Patients: A Novel Target of Thiazolidinediones
Background—Considerable evidence implicates the proinflammatory cytokine CD40 ligand (CD40L) in atherosclerosis and accumulating… Expand
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Highly Cited
2001
Highly Cited
2001
Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM
CD40 is a member of the tumor necrosis factor receptor superfamily, expressed on a wide range of cell types including B cells… Expand
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Highly Cited
1999
Highly Cited
1999
TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation
CD40 ligand (CD40L), a tumor necrosis factor (TNF) family member, plays a critical role in antigen-specific T cell responses in… Expand
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Highly Cited
1990
Highly Cited
1990
Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences.
Tumor necrosis factor (TNF) is a cytokine with a wide range of biological activities in inflammatory and immunologic responses… Expand
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Highly Cited
1990
Highly Cited
1990
Soluble forms of tumor necrosis factor receptors (TNF‐Rs). The cDNA for the type I TNF‐R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form…
Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory… Expand
Highly Cited
1989
Highly Cited
1989
A B‐lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
B cells and primary carcinomas express a surface molecule, Bp50 (CDw40), absent from other hematopoietic cells and from normal… Expand
Highly Cited
1989
Highly Cited
1989
Endocytosis and degradation of monoclonal antibodies targeting human B-cell malignancies.
Seven murine monoclonal antibodies (MoAbs) recognizing differentiation antigens present on B-lymphocytes were analyzed in… Expand
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Highly Cited
1988
Highly Cited
1988
Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.
CD20 is an antigen expressed on normal and malignant human B cells that is thought to function as a receptor during B cell… Expand
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