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CD40 Antigens

Known as: TNFRSF5 Receptor, Antigens, CD40 [Chemical/Ingredient], CDw40 Antigen 
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL… Expand
National Institutes of Health

Related topics

Related topics

41 relations
ApoptosisApoptosis Regulatory ProteinsB-Cell ActivationB-Lymphocytes
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Broader (1)

CD Antigens

Papers overview

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Highly Cited
2007
Highly Cited
2007
CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.
BACKGROUND Strong evidence supports a role for CD40 ligand (CD40L) as marker and mediator of inflammatory diseases such as… Expand
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Highly Cited
2006
Highly Cited
2006
An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions.
BACKGROUND Removal of stored supernatant abrogates most transfusion reactions to leukoreduced platelets (PLTs), suggesting that… Expand
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Highly Cited
2005
Highly Cited
2005
Associations between soluble CD40 ligand, atherosclerosis risk factors, and subclinical atherosclerosis: results from the Dallas Heart Study.
OBJECTIVE The purpose of this study was to evaluate the associations between plasma levels of soluble CD40 ligand (sCD40L… Expand
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Highly Cited
2003
Highly Cited
2003
Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones.
BACKGROUND Considerable evidence implicates the proinflammatory cytokine CD40 ligand (CD40L) in atherosclerosis and accumulating… Expand
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Highly Cited
2002
Highly Cited
2002
A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas.
B cell lineage non-Hodgkin's lymphomas (NHL-B) are neoplastic B cells that show dysregulated B lymphocyte growth characteristics… Expand
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Highly Cited
2001
Highly Cited
2001
Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM
CD40 is a member of the tumor necrosis factor receptor superfamily, expressed on a wide range of cell types including B cells… Expand
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Highly Cited
1999
Highly Cited
1999
TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation
CD40 ligand (CD40L), a tumor necrosis factor (TNF) family member, plays a critical role in antigen-specific T cell responses in… Expand
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Highly Cited
1998
Highly Cited
1998
Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells.
We analyzed the effect of CD40 triggering on the fludarabine-induced apoptosis of B chronic lymphocytic leukemia (B-CLL) cells… Expand
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Highly Cited
1990
Highly Cited
1990
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form…
Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory… Expand
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Highly Cited
1988
Highly Cited
1988
Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.
CD20 is an antigen expressed on normal and malignant human B cells that is thought to function as a receptor during B cell… Expand
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