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CD40 Antigens
Known as:
TNFRSF5 Receptor
, Antigens, CD40 [Chemical/Ingredient]
, CDw40 Antigen
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A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL…
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National Institutes of Health
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Related topics
Related topics
41 relations
Apoptosis
Apoptosis Regulatory Proteins
B-Cell Activation
B-Lymphocytes
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Broader (1)
CD Antigens
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
A Phase 1, Randomized Ascending Single‐Dose Study of Antagonist Anti‐Human CD40 ASKP1240 in Healthy Subjects
R. Goldwater
,
J. Keirns
,
+6 authors
J. Holman
American Journal of Transplantation
2013
Corpus ID: 22329646
This first‐in‐human, phase I study evaluated the safety, tolerability, pharmacokinetic and pharmacodynamic profile of ASKP1240 in…
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2008
2008
CD40‐CD40 ligand interactions in human microglia induce CXCL8 (interleukin‐8) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor‐κB (NFκB) and…
T. G. D’Aversa
,
E. Eugenin
,
J. Berman
Journal of Neuroscience Research
2008
Corpus ID: 26746211
CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated…
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2008
2008
Enhanced soluble CD40 ligand and Alzheimer's disease: Evidence of a possible pathogenetic role
G. Desideri
,
F. Cipollone
,
+8 authors
C. Ferri
Neurobiology of Aging
2008
Corpus ID: 24701223
2004
2004
Activated platelets rapidly up-regulate CD40L expression and can effectively mature and activate autologous ex vivo differentiated DC.
J. Martinson
,
J. Bae
,
H. Klingemann
,
Y. Tam
Cytotherapy
2004
Corpus ID: 28305868
Background DC are a promising immunotherapeutic for treatment of infectious/malignant disease. For clinical trials, immature DC…
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Highly Cited
2000
Highly Cited
2000
The Role of CD4+ T Cell Help and CD40 Ligand in the In Vitro Expansion of HIV-1-Specific Memory Cytotoxic CD8+ T Cell Responses
M. Ostrowski
,
S. Justement
,
+7 authors
A. Fauci
Journal of Immunology
2000
Corpus ID: 42035188
CD4+ T cells have been shown to play a critical role in the maintenance of an effective anti-viral CD8+ CTL response in murine…
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Highly Cited
1998
Highly Cited
1998
Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells
M. F. Romano
,
A. Lamberti
,
+8 authors
S. Venuta
1998
Corpus ID: 208530085
We analyzed the effect of CD40 triggering on the fludarabine-induced apoptosis of B chronic lymphocytic leukemia (B-CLL) cells…
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Highly Cited
1993
Highly Cited
1993
Expression of a 32‐kDa ligand for the CD40 antigen on activated human T lymphocytes
P. Hermann
,
D. Blanchard
,
+6 authors
J. Galizzi
European Journal of Immunology
1993
Corpus ID: 28214406
To identify the ligand(s) of the human CD40 antigen, a cDNA encoding the extracellular domain of the CD40 antigen was fused to a…
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Highly Cited
1992
Highly Cited
1992
Proliferation and differentiation of human CD5+ and CD5− B cell subsets activated through their antigen receptors or CD40 antigens
T. Defrance
,
B. Vanbervliet
,
I. Durand
,
J. Briolay
,
J. Banchereau
European Journal of Immunology
1992
Corpus ID: 20441299
The pan‐T cell antigen CD5 has been shown to delineate two different mouse B cell subsets, originating from distinct progenitors…
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Highly Cited
1989
Highly Cited
1989
Anti-CD45 inhibition of human B cell proliferation depends on the nature of activation signals and the state of B cell activation. A study with anti-IgM and anti-CDw40 antibodies.
M. Gruber
,
J. Bjorndahl
,
Seiji Nakamura
,
S. Fu
Journal of Immunology
1989
Corpus ID: 24725293
The proliferation of human peripheral and tonsillar B cells stimulated with the anti-CDw40 mAb 626.1 and/or anti-IgM antibody (Ab…
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Highly Cited
1988
Highly Cited
1988
Interleukin 4 and soluble CD23 as progression factors for human B lymphocytes: analysis of their interactions with agonists of the phosphoinositide “dual pathway” of signalling
J. Gordon
,
J. Cairns
,
M. Millsum
,
S. Gillis
,
G. Guy
European Journal of Immunology
1988
Corpus ID: 30291166
Human B lymphocytes pre‐activated for 24 h with a combination of phorbol dibutyrate [P(BU)2] and ionomycin were found to provide…
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