FAQ

CD40 Antigens

Known as: TNFRSF5 Receptor, Antigens, CD40 [Chemical/Ingredient], CDw40 Antigen 
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
051019872017

Related topics

Related topics

40 relations
ApoptosisApoptosis Regulatory ProteinsB-Cell ActivationB-Lymphocytes
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Broader (1)

CD Antigens

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
CD40 Antigens
Plasma membrane
Endothelial Cells
B-Lymphocytes
Monocytes
inflammatory response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.
OBJECTIVE Several lines of evidence implicate CD40 ligand (CD40L, CD154) as a mediator and marker of atherosclerosis. This study… (More)
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2003
2003
In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8+ T cell effector function in SV40 T antigen transgenic mice.
The ability to initiate and sustain CD8(+) T cell responses to tumors in vivo is hindered by the development of peripheral T cell… (More)
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Highly Cited
2002
Highly Cited
2002
CD40 regulates the processing of NF-kappaB2 p100 to p52.
The nf-kb2 gene encodes the cytoplasmic NF-kappaB inhibitory protein p100 from which the active p52 NF-kappaB subunit is derived… (More)
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Highly Cited
1995
Highly Cited
1995
Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes.
This study was initiated to explore the contribution of endogenous cytokines to CD40-induced B cell proliferation and… (More)
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Highly Cited
1993
Highly Cited
1993
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40.
In mice transgenic for an autoantibody, self-reactive B cells have been shown to be eliminated upon interaction with membrane… (More)
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Highly Cited
1990
Highly Cited
1990
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form…
Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory… (More)
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Highly Cited
1990
Highly Cited
1990
Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences.
Tumor necrosis factor (TNF) is a cytokine with a wide range of biological activities in inflammatory and immunologic responses… (More)
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Highly Cited
1989
Highly Cited
1989
A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
B cells and primary carcinomas express a surface molecule, Bp50 (CDw40), absent from other hematopoietic cells and from normal… (More)
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Highly Cited
1989
Highly Cited
1989
Endocytosis and degradation of monoclonal antibodies targeting human B-cell malignancies.
Seven murine monoclonal antibodies (MoAbs) recognizing differentiation antigens present on B-lymphocytes were analyzed in… (More)
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Highly Cited
1988
Highly Cited
1988
Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.
CD20 is an antigen expressed on normal and malignant human B cells that is thought to function as a receptor during B cell… (More)
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