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CD40 Antigens

Known as: TNFRSF5 Receptor, Antigens, CD40 [Chemical/Ingredient], CDw40 Antigen 
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL… 
National Institutes of Health

Related topics

Related topics

41 relations
ApoptosisApoptosis Regulatory ProteinsB-Cell ActivationB-Lymphocytes

Broader (1)

CD Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions
BACKGROUND: Removal of stored supernatant abrogates most transfusion reactions to leukoreduced platelets (PLTs), suggesting that… 
Highly Cited
1999
Highly Cited
1999
High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization.
Signaling by some TNF receptor family members, including CD40, is mediated by TNF receptor-associated factors (TRAFs) that… 
Highly Cited
1995
Highly Cited
1995
2 A crystal structure of an extracellular fragment of human CD40 ligand.
Highly Cited
1995
Highly Cited
1995
CD40 signaling-mediated induction of Bcl-XL, Cdk4, and Cdk6. Implication of their cooperation in selective B cell growth.
Signals sent through CD40 play crucial roles in B cell differentiation, including blocking apoptosis of germinal center B cells… 
Highly Cited
1991
Highly Cited
1991
Transmembrane signals generated through MHC class II, CD19, CD20, CD39, and CD40 antigens induce LFA-1-dependent and independent adhesion in human B cells through a tyrosine kinase-dependent pathway.
Transmembrane signals generated following mAb binding to CD19, CD20, CD39, CD40, CD43, Leu-13 Ag, and HLA-D region gene products… 
Highly Cited
1990
Highly Cited
1990
Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences.
Highly Cited
1989
Highly Cited
1989
Endocytosis and degradation of monoclonal antibodies targeting human B-cell malignancies.
Seven murine monoclonal antibodies (MoAbs) recognizing differentiation antigens present on B-lymphocytes were analyzed in… 
Highly Cited
1988
Highly Cited
1988
Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.
CD20 is an antigen expressed on normal and malignant human B cells that is thought to function as a receptor during B cell… 
Highly Cited
1988
Highly Cited
1988
Resting B lymphocytes can be triggered directly through the CDw40 (Bp50) antigen. A comparison with IL-4-mediated signaling.
Resting tonsillar B lymphocytes were shown to enlarge and become more buoyant when exposed to either IL-4 or a mAb (G28-5) to the… 
Highly Cited
1987
Highly Cited
1987
Augmentation of normal and malignant B cell proliferation by monoclonal antibody to the B cell-specific antigen BP50 (CDW40).
We recently described a 50,000 dalton polypeptide Bp50 (CDw40) that is expressed on human B cells and plays a role in regulating… 
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