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CD40 Antigens

Known as: TNFRSF5 Receptor, Antigens, CD40 [Chemical/Ingredient], CDw40 Antigen 
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL… 
National Institutes of Health

Related topics

Related topics

41 relations
ApoptosisApoptosis Regulatory ProteinsB-Cell ActivationB-Lymphocytes

Broader (1)

CD Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
A Phase 1, Randomized Ascending Single‐Dose Study of Antagonist Anti‐Human CD40 ASKP1240 in Healthy Subjects
This first‐in‐human, phase I study evaluated the safety, tolerability, pharmacokinetic and pharmacodynamic profile of ASKP1240 in… 
2008
2008
CD40‐CD40 ligand interactions in human microglia induce CXCL8 (interleukin‐8) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor‐κB (NFκB) and…
CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated… 
2004
2004
Activated platelets rapidly up-regulate CD40L expression and can effectively mature and activate autologous ex vivo differentiated DC.
Background DC are a promising immunotherapeutic for treatment of infectious/malignant disease. For clinical trials, immature DC… 
Highly Cited
2000
Highly Cited
2000
The Role of CD4+ T Cell Help and CD40 Ligand in the In Vitro Expansion of HIV-1-Specific Memory Cytotoxic CD8+ T Cell Responses
CD4+ T cells have been shown to play a critical role in the maintenance of an effective anti-viral CD8+ CTL response in murine… 
Highly Cited
1998
Highly Cited
1998
Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells
We analyzed the effect of CD40 triggering on the fludarabine-induced apoptosis of B chronic lymphocytic leukemia (B-CLL) cells… 
Highly Cited
1989
Highly Cited
1989
Anti-CD45 inhibition of human B cell proliferation depends on the nature of activation signals and the state of B cell activation. A study with anti-IgM and anti-CDw40 antibodies.
The proliferation of human peripheral and tonsillar B cells stimulated with the anti-CDw40 mAb 626.1 and/or anti-IgM antibody (Ab… 
Highly Cited
1988
Highly Cited
1988
Interleukin 4 and soluble CD23 as progression factors for human B lymphocytes: analysis of their interactions with agonists of the phosphoinositide “dual pathway” of signalling
Human B lymphocytes pre‐activated for 24 h with a combination of phorbol dibutyrate [P(BU)2] and ionomycin were found to provide… 
Highly Cited
1988
Highly Cited
1988
Soluble CD23 is released by B lymphocytes cycling in response to interleukin 4 and anti‐Bp50 (CDw40)
An enzyme‐linked immunoassay was developed to quantitate the production of soluble CD23 from cycling B lymphocytes. This molecule… 
1988
1988
Stimulation of B-chronic lymphocytic leukemia populations by recombinant interleukin-4 and other defined growth-promoting agents.
Monoclonal populations from 10 cases of phenotypically well-characterized B-chronic lymphocytic leukemia (B-CLL) and from a… 
1988
1988
Functional interaction between B cell subpopulations defined by CD23 expression
Using the CD23 monoclonal antibody (mAb) MHM6 and sheep anti‐mouse Ig bound to magnetic beads we have obtained highly purified… 
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