Recombinant CD40-Ligand

Known as: T-Cell Antigen gp39, T-BAM, rhu CD40L 
A recombinant therapeutic agent which is chemically identical to or similar to CD40-ligand. CD40-ligand, also known as CD40L/TRAP and CD154, is a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
This study presents evidence that human platelets bind lipopolysaccharide (LPS) from enterohemorrhagic Escherichia coli (EHEC… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Soluble CD40L (sCD40L), a substance that maximally reflects in vivo platelet activation, is increased in patients with… (More)
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Highly Cited
2003
Highly Cited
2003
The membrane-bound form of Fas ligand (FasL) signals apoptosis in target cells through engagement of the death receptor Fas… (More)
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Highly Cited
2002
Highly Cited
2002
CD40L, a member of the tumor necrosis factor family of ligands, plays a major role in immune responses via its receptor, CD40… (More)
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Highly Cited
2002
Highly Cited
2002
We have shown that interaction of CD40 with CD40L enables microglial activation in response to amyloid-β peptide (Aβ), which is… (More)
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Highly Cited
2000
Highly Cited
2000
In the present study, we investigated the role of the CD40L-CD40 pathway in a model of progressive atherosclerosis. ApoE-/- mice… (More)
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Highly Cited
1998
Highly Cited
1998
Increasing amounts of evidence support the involvement of inflammation and immunity in atherogenesis but mediators of… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Plaque disruption with thrombosis commonly causes the acute coronary syndromes. Macrophages, abundant at sites of… (More)
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Highly Cited
1996
Highly Cited
1996
The recent finding that CD40L on activated T cells induces interleukin (IL) 12 secretion in human peripheral blood monocytes in… (More)
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Highly Cited
1993
Highly Cited
1993
The ligand for CD40 (CD40L) is a membrane glycoprotein on activated T cells that induces B cell proliferation and immunoglobulin… (More)
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