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Recombinant CD40-Ligand

Known as: T-Cell Antigen gp39, T-BAM, rhu CD40L 
A recombinant therapeutic agent which is chemically identical to or similar to CD40-ligand. CD40-ligand, also known as CD40L/TRAP and CD154, is a… 
National Institutes of Health

Related topics

Related topics

11 relations
CD40 AntigensCD40 Ligand, humanCD40LG geneCD40LG wt Allele

Broader (1)

CD40 Ligand

Papers overview

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2014
2014
Immunotherapy reduces CD40L expression and modifies cytokine production in the CD4 cells of pollen allergy patients.
BACKGROUND Allergen-specific immunotherapy (SIT) is the only intervention for IgE-mediated respiratory disorders. OBJECTIVE The… 
2009
2009
Adenovirus-mediated CD40L gene therapy induced both humoral and cellular immunity against rat model of hepatocellular carcinoma
Highly Cited
2006
Highly Cited
2006
Soluble CD40L Levels Are Regulated by the −3459 A>G Polymorphism and Predict Myocardial Infarction and the Efficacy of Antithrombotic Treatment in Non-ST Elevation Acute Coronary Syndrome
Objectives—Current evidence suggests the CD40–CD40L pathway as a key process in the development, progression, and outcome of… 
2006
2006
CD40L proinflammatory and profibrotic effects on proximal tubular epithelial cells: role of NF-kappaB and lyn.
Chronic allograft nephropathy (CAN) is the main cause of renal graft loss, but its pathogenic mechanisms are still unclear… 
2004
2004
GP IIb/IIIa inhibition with eptifibatide lowers levels of soluble CD40L and RANTES after percutaneous coronary intervention
Platelets are the most abundant blood source of CD40L, a proinflammatory and prothrombotic costimulatory molecule implicated in… 
Review
2004
Review
2004
Costimulatory pathways as a basic mechanisms of activating a tolerance signal in T cells.
Immune tolerance is an active response leading to the T cell unresponsiveness in the presence of the graft, which may develop… 
2003
2003
Modulation of CD40L antigen expression in Jurkat cells: involvement of protein kinase C activity.
The CD40L expressed on activated CD4+ T cells delivers contact-dependent proliferative and anti-apoptotic signals to B… 
2002
2002
Cloning, sequencing and expression of porcine CD40 ligand in Escherichia coli and human and porcine cells.
The CD40L ligand (CD40L) plays an important role in the interaction between antigen-specific T lymphocytes and antigen-presenting… 
1999
1999
CD40L is necessary for the priming of effector cells for lymphocytic and granulomatous experimental autoimmune thyroiditis.
The interaction of CD40 on antigen presenting cells (APC) with CD40L on mouse thyroglobulin (MTg)-specific T cells may deliver an… 
1997
1997
A new multivalent B cell activation model--anti-IgD bound to Fc gamma RI: properties and comparison with CD40L-mediated activation.
CHO cells permanently transfected with mouse Fc gamma RI alpha chain were prepared and used as a model to polyclonally activate… 
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