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Hyper-IgM Immunodeficiency Syndrome, Type 1

Known as: HYPER-IgM SYNDROME, Immunodeficiencies, X-Linked Hyper-IgM, Syndrome, HIGM1 
An X-linked hyper-IgM immunodeficiency subtype resulting from mutation in the gene encoding CD40 LIGAND.
National Institutes of Health

Related topics

Related topics

23 relations
Anemia, HemolyticCD40 Ligand, humanCD40LG, 1-BP INS, TTT-TTTT, FS84TERCD40LG, SER128ARG AND GLU129GLY

Narrower (1)

HYPER-IgM IMMUNODEFICIENCY, X-LINKED, WITH ECTODERMAL DYSPLASIA, HYPOHIDROTIC

Broader (1)

Immunologic Deficiency Syndromes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Autoimmunity, autoinflammation and lymphoma in combined immunodeficiency (CID).
Highly Cited
2004
Highly Cited
2004
Effect of exercise timing on postprandial lipemia in hypertriglyceridemic men.
We investigated the effect of exercise timing on attenuation of postprandial hyper-triglyceridemia (PHTG) in individuals with… 
Highly Cited
1999
Highly Cited
1999
Probing the symmetry of the nonlinear optic chromophore Ru(trans-4,4'- diethylaminostyryl-2,2'-bipyridine)32+: Insight from polarized hyper- Rayleigh scattering and electroabsorption (Stark…
Polarized hyper-Rayleigh scattering (HRS) has been used to interrogate a putative octupolar “super” chromophore Ru(trans-4,4… 
Highly Cited
1998
Highly Cited
1998
Circadian Hyper-Amplitude-Tension (CHAT): A Disease Risk Syndrome of Anti-Aging Medicine
Serial measurements, taken around the clock in the laboratory and clinic, can be analyzed by computer-implemented curve-fitting… 
Highly Cited
1996
Highly Cited
1996
Regulation of B cell survival in xid mice by the proto-oncogene bcl-2.
CBA/N mice carry an X-linked immunodeficiency (xid) due to a point mutation in the Bruton's tyrosine kinase (btk) gene. xid mice… 
Highly Cited
1994
Highly Cited
1994
Genomic organization of mouse and human Bruton's agammaglobulinemia tyrosine kinase (Btk) loci.
Btk is a cytoplasmic protein tyrosine kinase (PTK) that has been directly implicated in the pathogenesis of X-linked… 
1991
1991
The SCID-hu mouse and thyroid autoimmunity: characterization of human thyroid autoantibody secretion.
Highly Cited
1990
Highly Cited
1990
Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome.
The hyper-IgE (HIE) syndrome is characterized by high IgE serum levels, chronic dermatitis, and recurrent infections. The… 
1987
1987
Development of B lymphocytes in mice heterozygous for the X-linked immunodeficiency (xid) mutation. xid inhibits development of all splenic and lymph node B cells at a stage subsequent to their…
CBA/N mice were crossed with CBA/Ca-Pgk-1a to produce female F1 hybrids that were heterozygous for both xid and the… 
Highly Cited
1984
Highly Cited
1984
Results of transvesical infiltration of the pelvic plexuses with phenol in 116 patients.
One hundred and sixteen patients with detrusor instability, detrusor hyper-reflexia or bladder hypersensitivity who had failed to… 
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