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GENERAL INTRODUCTION
  • H. Kunkel
  • Medicine
  • The Journal of experimental medicine
  • 1 September 1971
Partly based on: " Gray matter damage in multiple sclerosis: impact on clinical symptoms "
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Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus.
Sera of patients with systemic lupus erythematosus were demonstrated to contain precipitating antibodies to soluble tissue components other than DNA. One dominant reaction was observed which wasExpand
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Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells
Human T-cell blasts were generated by stimulation with mitogens and antigens. A proportion of these blasts expressed Ia antigens detectable by immunofluorescence with both allo- andExpand
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Individual Antigenic Specificity of Isolated Antibodies
Antisera produced against certain isolated human antibodies showed clear antigenic differences between these antibodies. Individual antigenic specificity was demonstrated for two anti-A antibodies,Expand
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AN UNUSUAL PROTEIN COMPONENT OF HIGH MOLECULAR WEIGHT IN THE SERUM OF CERTAIN PATIENTS WITH RHEUMATOID ARTHRITIS
In the sera of a number of patients with rheumatoid arthritis an unusual, high molecular weight protein component could be detected by direct ultracentrifuge analysis of whole serum. This materialExpand
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Alterations of estrogen metabolism in systemic lupus erythematosus.
Estradiol metabolism in 10 patients with systemic lupus erythematosus (SLE) and 29 normal controls was studied by measurement of urinary metabolites after injection of labeled 3H-estradiol. PatientsExpand
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Deoxyribonucleic Acid ( DNA ) and Antibodies to DNA in the Serum of Patients with Systemic Lupus Erythematosus *
Although antibodies to deoxyribonucleic acid (DNA) and to many other cell constituents have been described in patients with systemic lupus erythematosus (SLE), the relationship of these antibodies toExpand
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IMMUNOLOGICAL STUDIES CONCERNING THE NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
Antibodies were eluted from the isolated glomeruli prepared from the kidneys of 10 patients with the nephritis of systemic lupus erythematosus. Antibodies reacting primarily with buffer extracts ofExpand
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Isolation of a Thermolabile Serum Protein which Precipitates γ-Globulin Aggregates and Participates in Immune Hemolysis.∗
Summary A protein of normal human serum capable of precipitating soluble aggregates of γ-globulin was isolated and found to be a euglobulin with an S° 20.w = 11 S and the approximate electrophoreticExpand
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