Skip to search formSkip to main contentSkip to account menu

Hydroxymethylglutaryl coenzyme A reductase

Known as: Hydroxymethylglutaryl-Coenzyme A Reductase (NADP), 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent, Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent 
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.
National Institutes of Health

Related topics

Related topics

11 relations
3-hydroxy-3-methylglutaryl coenzyme A reductase activityHMGCR geneIn BloodProcess of secretion

Narrower (2)

HMGCR protein, humanHMGR protein, Arabidopsis

Broader (1)

Hydroxymethylglutaryl-CoA reductase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Improvement of thermal stability of Leuconostoc pseudomesenteroides glucose-6-phosphate dehydrogenase
Glucose-6-phosphate dehydrogenase (G6PDH, EC 1.1.1.49) from Leuconostoc pseudomesenteroides (the previously named: Leuconostoc… 
2002
2002
Hydroxymethylglutaryl-coenzyme A Reductase Inhibitors (statins) VHA Pharmacy Benefits Management Strategic Healthcare Group and the Medical Advisory Panel
Coronary heart disease (CHD) continues to be the leading cause of mortality and a significant cause of morbidity among Americans… 
1986
1986
Effect of Pentagastrin, Secretin and Cholecystokinin on Growth and Differentiation in Organ Cultured Rabbit Small Intestine
The effect of pentagastrin, secretin and cholecystokinin on biochemical parameters of mucosal growth and differentiation was… 
1984
1984
In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone.
It has been previously demonstrated that the enzymic activity of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG… 
1984
1984
Hydroxymethylglutaryl CoA reductase and the modulation of microsomal cholesterol content by the nonspecific lipid transfer protein.
The influence of membrane cholesterol content on 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase, EC 1.1.1.34) in rat… 
1982
1982
Production and characterization of monoclonal antibodies to rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase [HMG-CoA reductase; mevalonate:NADP+ oxidoreductase (CoA-acylating… 
1981
1981
Effect of candicidin on cholesterol and bile acid metabolism in the rat
Sterol metabolism studies were carried out in rats maintained on a diet containing a polyene antibiotic, candicidin, (30 mg/kg… 
Highly Cited
1977
Highly Cited
1977
Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7alpha-hydroxylase activities.
Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7alpha-hydroxylase activities in rat… 
1970
1970
Intrazelluläre Lokalisation von Enzymen des Flußkrebses
SummaryProperties of the mitochondria from the crayfish have been investigated. Buffered 0,1 M KCl with 0,001 M ATP proved to be… 
1959
1959
The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. I. Identification and purification of the hydroxymethylglutaryl coenzymecondensing enzyme.