Hydroxymethylglutaryl coenzyme A reductase

Known as: Hydroxymethylglutaryl-Coenzyme A Reductase (NADP), 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent, Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent 
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.
National Institutes of Health

Papers overview

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2013
2013
We have examined the role that hydroxymethylglutaryl coenzyme A reductase (HMGCR) plays during respiratory syncytial virus (RSV… (More)
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2006
2006
BACKGROUND Although highly controversial, directto-consumer (DTC) television advertising for prescription drugs is an established… (More)
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Highly Cited
2002
Highly Cited
2002
Reductase Inhibitor, Improves Endothelial Function in Elderly Diabetic Patients Within 3 Days To the Editor: In the July 24, 2001… (More)
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2002
2002
BACKGROUND Patients with cardiac hypertrophy are at increased cardiovascular risk. It has been hypothesized that… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Recent studies have supported the hypothesis that calcific aortic stenosis is the product of an active inflammatory… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Elevated oxidative stress and superoxide anion formation in vascular cells could promote conversion of LDL to… (More)
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Highly Cited
2001
Highly Cited
2001
Apolipoprotein B has been shown to be a better predictor of coronary heart disease than low-density lipoprotein (LDL) cholesterol… (More)
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Highly Cited
1997
Highly Cited
1997
The aldo-keto reductases (AKRs) represent a growing oxidoreductase superfamily. Forty proteins have been identified and… (More)
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Highly Cited
1987
Highly Cited
1987
The possibility that the serum concentrations of various cholesterol precursors may reflect the activity of the hepatic HMG-CoA… (More)
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1983
1983
Extensive studies have demonstrated that the normal inhibition of cholesterol synthesis by cholesterol feeding is decreased in… (More)
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