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Hydroxymethylglutaryl coenzyme A reductase

Known as: Hydroxymethylglutaryl-Coenzyme A Reductase (NADP), 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent, Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent 
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Hesperetin is a naturally occurring flavonoid that has hypolipidemic properties. METHODS Male rats were fed a 1 g… Expand
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Highly Cited
2001
Highly Cited
2001
Background—Recent studies have supported the hypothesis that calcific aortic stenosis is the product of an active inflammatory… Expand
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Highly Cited
2001
Highly Cited
2001
Background—Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) attenuate angiotensin II-induced cellular signaling… Expand
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Highly Cited
2001
Highly Cited
2001
Background—Elevated oxidative stress and superoxide anion formation in vascular cells could promote conversion of LDL to… Expand
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Highly Cited
2001
Highly Cited
2001
Background— The short-term effects of hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) on endothelial function at… Expand
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Highly Cited
2001
Highly Cited
2001
Apolipoprotein B has been shown to be a better predictor of coronary heart disease than low-density lipoprotein (LDL) cholesterol… Expand
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Highly Cited
1997
Highly Cited
1997
The aldo-keto reductases (AKRs) represent a growing oxidoreductase superfamily. Forty proteins have been identified and… Expand
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Highly Cited
1997
Highly Cited
1997
Oryzanol is a class of nonsaponifiable lipids of rice bran oil (RBO). More specifically, oryzanol is a group of ferulic acid… Expand
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Highly Cited
1990
Highly Cited
1990
BACKGROUND Inhibitors of the rate-limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA… Expand
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Highly Cited
1987
Highly Cited
1987
The possibility that the serum concentrations of various cholesterol precursors may reflect the activity of the hepatic HMG-CoA… Expand
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