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Hydroxymethylglutaryl coenzyme A reductase

Known as: Hydroxymethylglutaryl-Coenzyme A Reductase (NADP), 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent, Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent 
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.
National Institutes of Health

Papers overview

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2014
2014
Hypolipidemic and antioxidant activity profiles of ethanolic extracts of Symplocos racemosa (EESR) were studied by triton-WR1339… 
2004
2004
SummaryInhibitors of hydroxymethylglutaryl coenzyme A reductase are used clinically to decrease blood levels of low-density… 
Highly Cited
1999
Highly Cited
1999
There is no consensus whether hepatic lipid regulatory enzymes play primary or secondary roles in cholesterol cholelithiasis. We… 
Highly Cited
1990
Highly Cited
1990
Under most experimental conditions, the activities of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA reductase) and cholesterol 7… 
Highly Cited
1988
Highly Cited
1988
Bile acid synthesis is thought to be regulated by a negative feedback mechanism which is presumably dependent upon the flux of… 
Highly Cited
1988
Highly Cited
1988
In the normal fed rat, both 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) synthase and HMG-CoA reductase are found in high… 
Highly Cited
1986
Highly Cited
1986
We here report the isolation and nucleotide sequencing of a full-length 3.3-kilobase cDNA for the cytoplasmic form of 3-hydroxy-3… 
Highly Cited
1977
Highly Cited
1977
Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7alpha-hydroxylase activities in rat… 
1974
1974
RECENT evidence indicates that sterol biosynthesis from acetate, but not from mevalonate, increases several-fold in the…