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Hydroxymethylglutaryl-CoA reductase

Known as: Hydroxymethylglutaryl coenzyme A reductases, 3 Hydroxy 3 methylglutaryl CoA Reductase, hmg-coa reductase 
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
In light of accumulating evidence that aggressive LDL-lowering therapy may offer increased protection against coronary heart… 
Highly Cited
2006
Highly Cited
2006
Statins, the most widely prescribed cholesterol-lowering drugs, are considered to be first-line therapeutics for the prevention… 
Review
2002
Review
2002
OBJECTIVE: To evaluate the use and potential benefit of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins… 
2002
2002
1. Inhibitors of 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase (statins) reduce serum cholesterol and have proven… 
Highly Cited
1999
Highly Cited
1999
There is no consensus whether hepatic lipid regulatory enzymes play primary or secondary roles in cholesterol cholelithiasis. We… 
Highly Cited
1979
Highly Cited
1979
A simple and rapid mixed-phase method for the quantitative assay of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase and a…