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Hydro-Lyases

Known as: hydrase, hydro lyase, Dehydratases 
Enzymes that catalyze the breakage of a carbon-oxygen bond leading to unsaturated products via the removal of water. EC 4.2.1.
National Institutes of Health

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Narrower (46)

(R)-2-methylmalate dehydratase(S)-2-methylmalate dehydratase2,2-dimethylcyclopropanecarbonitrile hydratase, Rhodococcus boritolerans2-hydroxypentadienoic acid hydratase
In BloodProcess of secretionantagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
1979
Highly Cited
1979
Epoxide hydrase and glutathione S-transferase activities with selected alkene and adrene oxides in several marine species.
Highly Cited
1977
Highly Cited
1977
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls.
Highly Cited
1977
Highly Cited
1977
Stereospecificity of microsomal and purified epoxide hydrase from rat liver. Hydration of arene oxides of polycyclic hydrocarbons.
Highly Cited
1976
Highly Cited
1976
Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.
Highly Cited
1976
Highly Cited
1976
Hepatic and extrahepatic metabolism, in vitro, of an epoxide (8-(14) C-styrene oxide) in the rabbit.
Highly Cited
1975
Highly Cited
1975
Liver microsomal expoxide hydrase. Solubilization, purification, and characterization.
Highly Cited
1975
Highly Cited
1975
Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450.
Highly Cited
1975
Highly Cited
1975
The benzo(alpha)pyrene deoxyribonucleoside products isolated from DNA after metabolism of benzo(alpha)pyrene by rat liver microsomes in the presence of DNA.
Rat liver microsomes (induced by 3-methylcholanthrene) were used to catalyze the binding of tritium-labeled benzo(alpha)pyrene to… 
Highly Cited
1973
Highly Cited
1973
The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives.
Highly Cited
1971
Highly Cited
1971
Solubilization, purification, and properties of a hepatic epoxide hydrase.
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