HTT gene

Known as: HD GENE, HUNTINGTIN, IT15 
This gene may be involved in vesicle transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
010020019882017

Papers overview

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Highly Cited
2007
Highly Cited
2007
Trehalose, a disaccharide present in many non-mammalian species, protects cells against various environmental stresses. Whereas… (More)
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Highly Cited
2006
Highly Cited
2006
Huntington's disease (HD) is an inherited neurodegenerative disease caused by a glutamine repeat expansion in huntingtin protein… (More)
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Highly Cited
2003
Highly Cited
2003
Huntingtin protein is mutated in Huntington disease. We previously reported that wild-type but not mutant huntingtin stimulates… (More)
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Highly Cited
2001
Highly Cited
2001
Intracellular deposition of aggregated and ubiquitylated proteins is a prominent cytopathological feature of most… (More)
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Highly Cited
2001
Highly Cited
2001
Huntingtin is a 350-kilodalton protein of unknown function that is mutated in Huntington's disease (HD), a neurodegenerative… (More)
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Highly Cited
1999
Highly Cited
1999
Huntington's disease (HD) is an inherited, neurodegenerative disorder caused by the expansion of a glutamine repeat in the N… (More)
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Highly Cited
1999
Highly Cited
1999
The data we report in this study concern the types, location, numbers, forms, and composition of microscopic huntingtin… (More)
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Highly Cited
1998
Highly Cited
1998
The mechanisms by which mutant huntingtin induces neurodegeneration were investigated using a cellular model that recapitulates… (More)
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Highly Cited
1997
Highly Cited
1997
The cause of neurodegeneration in Huntington's disease (HD) is unknown. Patients with HD have an expanded NH2-terminal… (More)
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Highly Cited
1997
Highly Cited
1997
The mechanism by which an elongated polyglutamine sequence causes neurodegeneration in Huntington's disease (HD) is unknown. In… (More)
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