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HTT gene

Known as: HD GENE, HUNTINGTIN, IT15 
This gene may be involved in vesicle transport.
National Institutes of Health

Related topics

Related topics

6 relations
HD protein, humanHomo sapiensHuntington DiseaseLigand Binding

Narrower (1)

HTT wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Influence of species differences on the neuropathology of transgenic Huntington's disease animal models.
2007
2007
BH3‐only proteins Bid and BimEL are differentially involved in neuronal dysfunction in mouse models of Huntington's disease
Apoptosis, a cell death mechanism regulated by Bcl‐2 family members, has been proposed as one of the mechanisms leading to… 
2006
2006
Genetic analysis of candidate genes modifying the age-at-onset in Huntington’s disease
The expansion of a polymorphic CAG repeat in the HD gene encoding huntingtin has been identified as the major cause of Huntington… 
Highly Cited
2005
Highly Cited
2005
Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment
Highly Cited
2005
Highly Cited
2005
Modulation of age at onset of Huntington disease patients by variations in TP53 and human caspase activated DNase (hCAD) genes
Highly Cited
2003
Highly Cited
2003
Expression of Mutant Huntingtin Blocks Exocytosis in PC12 Cells by Depletion of Complexin II*
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by an expanded CAG repeat in the HD gene. We… 
Highly Cited
2002
Highly Cited
2002
Maintenance of Susceptibility to Neurodegeneration Following Intrastriatal Injections of Quinolinic Acid in a New Transgenic Mouse Model of Huntington's Disease
A transgenic mouse model of Huntington's disease (R6/1 and R6/2 lines) expressing exon 1 of the HD gene with 115-150 CAG repeats… 
Highly Cited
1999
Highly Cited
1999
Corrigendum: Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin (Human Molecular Genetics (1999) 8 (397-407))
Review
1999
Review
1999
Recent Insights into the Molecular Pathogenesis of Huntington Disease
in vitro 
Review
1998
Review
1998
Molecular aspects of Huntington's disease
Huntington's disease (HD) is a progressive neurodegenerative disease striking principally medium spiny GABAergic neurons of the… 
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