HD protein, human

Known as: Huntington disease protein, human, HTT protein, human, Huntingtin 
Huntingtin (3144 aa, ~348 kDa) is encoded by the human HTT gene. This protein may be involved in the regulation of vesicular transport.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The transcription factor REST silences neuronal gene expression in non-neuronal cells. In neurons, the protein is sequestered in… (More)
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Highly Cited
2006
Highly Cited
2006
Huntington's disease (HD) is an inherited neurodegenerative disease caused by a glutamine repeat expansion in huntingtin protein… (More)
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Highly Cited
2004
Highly Cited
2004
Polyglutamine expansion (polyQ) in the protein huntingtin is pathogenic and responsible for the neuronal toxicity associated with… (More)
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Highly Cited
2004
Highly Cited
2004
Huntington's disease (HD) is characterized by the accumulation of a pathogenic protein, Huntingtin (Htt), that contains an… (More)
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Highly Cited
2003
Highly Cited
2003
We tested whether proteins implicated in Huntington's and other polyglutamine (polyQ) expansion diseases can cause axonal… (More)
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Highly Cited
2002
Highly Cited
2002
Huntington's disease (HD) is caused by an expansion of exonic CAG triplet repeats in the gene encoding huntingtin protein (Htt… (More)
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Highly Cited
2002
Highly Cited
2002
Huntington's disease (HD) is an inherited neurodegenerative disease caused by expansion of a polyglutamine tract in the… (More)
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Highly Cited
2001
Highly Cited
2001
Huntingtin is a 350-kilodalton protein of unknown function that is mutated in Huntington's disease (HD), a neurodegenerative… (More)
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Highly Cited
1998
Highly Cited
1998
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder. Disease alleles contain a trinucleotide repeat… (More)
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Highly Cited
1995
Highly Cited
1995
The gene defective in Huntington's disease encodes a protein, huntingtin, with unknown function. Antisera generated against three… (More)
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