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Huntington Disease

Known as: Huntington Chorea, Progressive Chorea, Hereditary, Chronic (Huntington), Huntington Disease [Disease/Finding] 
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
  • D. Selkoe
  • Cold Spring Harbor perspectives in biology
  • 2011
  • Corpus ID: 117081
Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic… Expand
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Review
2011
Review
2011
Huntington's disease is a progressive, fatal, neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene… Expand
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Review
2007
Review
2007
Huntington's disease may present at any age, but most typically manifests between the ages of 35 and 45 years as a slowly… Expand
Highly Cited
2004
Highly Cited
2004
Huntington disease is one of nine inherited neurodegenerative disorders caused by a polyglutamine tract expansion. Expanded… Expand
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Highly Cited
2001
Highly Cited
2001
Huntingtin is a 350-kilodalton protein of unknown function that is mutated in Huntington's disease (HD), a neurodegenerative… Expand
Highly Cited
1996
Highly Cited
1996
! The Unified Huntington’s Disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of… Expand
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Highly Cited
1996
Highly Cited
1996
The Unified Huntington's disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of clinical… Expand
Highly Cited
1986
Highly Cited
1986
Huntington's disease (HD) is an autosomal dominant neurological disorder characterized by progressive chorea, cognitive… Expand
Highly Cited
1985
Highly Cited
1985
In postmortem brain specimens from 163 clinically diagnosed cases of Huntington's disease (HD) the striatum exhibited marked… Expand
Highly Cited
1983
Highly Cited
1983
Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The… Expand