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Baclofen

Known as: Chlorophenyl GABA, Baclofenum, beta-(4-Chlorophenyl)gaba 
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Recent clinical trials and case-reports indicate that baclofen, a GABA(B) agonist, may have efficacy for alcohol… 
Highly Cited
2002
Highly Cited
2002
AIMS The gamma-aminobutyric acid (GABA(B)) receptor agonist, baclofen, has recently been shown to reduce alcohol intake in… 
Review
2000
Review
2000
  • J. Bormann
  • TIPS - Trends in Pharmacological Sciences
  • 2000
  • Corpus ID: 45803665
Highly Cited
1998
Highly Cited
1998
We observed a marked prolongation of the transcranially evoked silent period during continuous intrathecal administration of high… 
Highly Cited
1991
Highly Cited
1991
Seventeen patients with congenital spastic cerebral palsy and six patients with other forms of spasticity were injected… 
Highly Cited
1989
Highly Cited
1989
We studied the effect of the intrathecal infusion of baclofen, an agonist of gamma-aminobutyric acid, on abnormal muscle tone and… 
Highly Cited
1984
Highly Cited
1984
A double‐blind crossover study of the effects of baclofen was conducted on 10 patients with typical trigeminal neuralgia… 
Highly Cited
1981
Highly Cited
1981
The presence of a novel receptor for the neurotransmitter γ-aminobutyric acid (GABA) on peripheral autononric nerve terminals and… 
Highly Cited
1980
Highly Cited
1980
The existence of a receptor for γ-aminobutyric acid (GABA) on neurones of the mammalian central nervous system (CNS) is now…