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HSPA5 protein, human

Known as: Endoplasmic Reticulum Lumenal Ca(2+)-Binding Protein grp78, heat shock 70kDa protein 5, human, Immunoglobulin Heavy Chain-Binding Protein 
78 kDa glucose-regulated protein (654 aa, ~72kDa) is encoded by HSPA5 gene. The protein is intracellularly localized in the endoplasmic reticulum… 
National Institutes of Health

Related topics

Related topics

10 relations
Endoplasmic ReticulumHSPA5 geneHSPA5 wt AlleleNegative Regulation of Apoptosis

Broader (1)

molecular chaperone GRP78

Papers overview

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2015
2015
Amino-terminal arginylation as a degradation signal for selective autophagy
The ubiquitin-proteasome system and the autophagy lysosome system are the two major protein degradation machineries in eukaryotic… 
2009
2009
Involvement of GRP78 in inhibition of HBV secretion by Boehmeria nivea extract in human HepG2 2.2.15 cells
Summary.  Previous studies showed that the root extract of Boehmeria nivea (BNE) can significantly suppress the production of… 
2008
2008
The endoplasmic reticulum stress of placental impoverishment.
This Commentary discusses the key roles of protein synthesis-inhibition and endoplasmic reticulum (ER) stress in the… 
2007
2007
Regulatory proteins of eukaryotic initiation factor 2‐alpha subunit (eIF2α) phosphatase, under ischemic reperfusion and tolerance
Phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α), which is one of the substrates of protein… 
2007
2007
Ethyl 2- [N-m-chlorobenzyl- (2'-methyl)] anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOT01006) induces apoptosis in human cervical cancer HeLa cells.
Human cervical cancer is potentially lethal, and therefore the development of effective and tolerable therapeutic options is… 
2007
2007
Cocaine increases immunoglobulin heavy chain binding protein and caspase-12 expression in the rat dorsal striatum
RationaleCocaine increases endoplasmic reticulum (ER) stress protein expression via glutamate and dopamine receptor activation in… 
1994
1994
A 69 kDa immunodominant antigen of Trypanosoma (Nannomonas) congolense is homologous to immunoglobulin heavy chain binding protein (BiP)
SUMMARY An immunodominant antigen in Trypanosoma congolense-infected cattle is a 69 kDa protein which is conserved among species… 
1993
1993
Relationship between defective mouse mammary tumor virus envelope glycoprotein synthesis and GRP78 synthesis in glucocorticoid-treated mouse lymphoma cells. Evidence for translational control of…
1991
1991
Calcium-dependent autophosphorylation of the glucose-regulated protein, Grp78.
1991
1991
Targeting and assembly of an oligomeric bacterial enterotoxoid in the endoplasmic reticulum of Saccharomyces cerevisiae
A hybrid protein consisting of the Escherichia coli lipoprotein signal sequence attached to the mature sequence of the B subunit… 
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