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HSPA5 wt Allele

Known as: D7G6, GRP78, IGH-BIP Gene 
Human HSPA5 wild-type allele is located within 9q34 and is approximately 6 kb in length. This allele, which encodes 78 kDa glucose-regulated protein… 
National Institutes of Health

Related topics

Related topics

10 relations
9q34HSPA5 protein, humanNegative Regulation of ApoptosisPrion Disease Pathway

Broader (1)

HSPA5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Association of GRP78, HIF-1α and BAG3 Expression with the Severity of Chronic Lymphocytic Leukemia.
INTRODUCTION Parallel with the progression of Chronic Lymphocytic Leukemia (CLL), the levels of 78KDa Glucose-Regulated Protein… 
2018
2018
Genetic association of promoter in GRP78 gene with nasopharyngeal carcinoma in a Chinese population
BackgroundEmerging evidences were accumulated to support the view that GRP78 might be associated with multiple types of cancer… 
2015
2015
The Expression and Clinical Pathological Significances of GRP78 in Human Gastric Cancer Tissues
Objective To explore the role of GRP78 in the development of gastric carcinoma by analysis of the expression of GRP78 in gastric… 
2015
2015
Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159
Overexpression of the GRP78 receptor on cell surfaces has been linked with tumor growth, metastasis, and resistance to therapy… 
2015
2015
GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer
Purpose We investigated the relationships between biomarkers related to endoplasmic reticulum stress proteins (glucose-regulated… 
2012
2012
The Involvement of GRP78 on Estrogen Signaling in Gastric Cancer
It has been reported that GRP78 is highly expressed in gastric cancer, and it is considered as a marker for cancer progression… 
2000
2000
Thapsigargin‐induced grp78 expression is mediated by the increase of cytosolic free calcium in 9L rat brain tumor cells
Exposure of 9L rat brain tumor cells to 300 nM thapsigargin (TG), a sarcoendoplasmic Ca2+‐ATPases inhibitor, leads to an… 
Highly Cited
1999
Highly Cited
1999
Glucose-related protein (GRP78) and its relationship to the drug-resistance proteins P170, GST-pi, LRP56 and angiogenesis in non-small cell lung carcinomas.
Several studies have documented that induction of the glucose-related protein (GRP78) is associated with the development of drug… 
1997
1997
Reduction of trans-4,5-Dihydroxy-1,2-dithiane by Cellular Oxidoreductases Activates gadd153/chop andgrp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells*
trans-4,5-Dihydroxy-1,2-dithiane, the intramolecular disulfide form of dithiothreitol (DTTox) transcriptionally activates the… 
1991
1991
Calcium-dependent autophosphorylation of the glucose-regulated protein, Grp78.
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