Prion Disease Pathway

Known as: Prion Disease 
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2015
0519932015

Papers overview

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Highly Cited
2012
Highly Cited
2012
Prion diseases are transmissible neurodegenerative disorders affecting both humans and animals. The cellular prion protein, PrP(C… (More)
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2011
2011
The transmissible agent of prion disease consists of a prion protein in its abnormal, β-sheet rich state (PrP(Sc)), which is… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE The objective of the study is to report 2 new genotypic forms of protease-sensitive prionopathy (PSPr), a novel prion… (More)
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Highly Cited
2009
Highly Cited
2009
Prion disease is a neurodegenerative malady, which is believed to be transmitted via a prion protein in its abnormal conformation… (More)
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2008
2008
The trafficking of normal cellular prion protein (PrPC) is believed to control its conversion to the altered conformation… (More)
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Highly Cited
2008
Highly Cited
2008
Disease-related PrP(Sc) [pathogenic PrP (prion protein)] is classically distinguished from its normal cellular precursor, PrP(C… (More)
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Highly Cited
2007
Highly Cited
2007
The mechanism of cell death in prion disease is unknown but is associated with the production of a misfolded conformer of the… (More)
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Highly Cited
2003
Highly Cited
2003
Much evidence supports the hypothesis that the infectious agents of prion diseases are devoid of nucleic acid, and instead are… (More)
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Highly Cited
2002
Highly Cited
2002
The outbreak of new variant Creutzfeldt-Jakob disease has raised the specter of a potentially large population being at risk to… (More)
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2002
2002
Sheep is a unique example among mammalian species to present a strong correlation between genotype and prion disease… (More)
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