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Prion Disease Pathway

Known as: Prion Disease 
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Prion disorders are transmissible diseases caused by a proteinaceous infectious agent that can infect the lymphatic and nervous… Expand
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2013
2013
Prions are infectious agents causing fatal neurodegenerative diseases of humans and animals. In humans, these have sporadic… Expand
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Highly Cited
2012
Highly Cited
2012
Increasing evidence supports the involvement of microRNAs (miRNAs) in inflammatory and immune processes in prion… Expand
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2012
2012
Each known abnormal prion protein (PrPSc) is considered to have a specific range and therefore the ability to infect some species… Expand
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2012
2012
Mammalian species vary widely in their apparent susceptibility to prion diseases. For example, several felid species developed… Expand
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Highly Cited
2011
Highly Cited
2011
The transmissible agent of prion disease consists of a prion protein in its abnormal, β-sheet rich state (PrPSc), which is… Expand
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2010
2010
Disease-related prion protein, PrPSc, is classically distinguished from its normal cellular precursor, PrPC, by its detergent… Expand
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Highly Cited
2009
Highly Cited
2009
Prion disease is a neurodegenerative malady, which is believed to be transmitted via a prion protein in its abnormal conformation… Expand
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Highly Cited
2009
Highly Cited
2009
Prions cause transmissible neurodegenerative diseases and replicate by conformational conversion of normal benign forms of prion… Expand
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Highly Cited
2003
Highly Cited
2003
Much evidence supports the hypothesis that the infectious agents of prion diseases are devoid of nucleic acid, and instead are… Expand
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