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molecular chaperone GRP78

Known as: immunoglobulin heavy chain-binding protein, BiP, Ig heavy chain binding protein, Ig heavy chain binding protein 
National Institutes of Health

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Related topics

5 relations
HSPA5 geneHSPA5 wt Allele

Narrower (2)

HSPA5 protein, humanHspa5 protein, mouse

Broader (1)

Heat shock proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Triptolide induces p53‐dependent cardiotoxicity through mitochondrial membrane permeabilization in cardiomyocytes
2014
2014
New low molecular weight polycation-based nanoparticles for effective codelivery of pDNA and drug.
The development of new cationic nanoparticles that are safe and effective for biomedical applications has attracted considerable… 
2014
2014
The BiP Cochaperone ERdj4 Is Required for B Cell Development and Function
ERdj4 is a BiP cochaperone regulated by the unfolded protein response to facilitate degradation of unfolded and/or misfolded… 
Highly Cited
2013
Highly Cited
2013
Synergistic enhancement of cancer therapy using a combination of heat shock protein targeted HPMA copolymer-drug conjugates and gold nanorod induced hyperthermia.
2012
2012
Endoplasmic reticulum stress and C/EBP homologous protein-induced Bax translocation are involved in angiotensin II-induced apoptosis in cultured neonatal rat cardiomyocytes
The aim of this study was to identify the roles and potential mechanisms of endoplasmic reticulum stress (ER stress… 
Highly Cited
2011
Highly Cited
2011
UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression.
Endocrine pancreas from pregnant rats undergoes several adaptations that comprise increase in β-cell number, mass and insulin… 
Highly Cited
2010
Highly Cited
2010
Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells.
Highly Cited
2010
Highly Cited
2010
Organization of the Sec61 translocon, studied by high resolution native electrophoresis.
Cotranslational translocation of polypeptides into the ER is controlled by the dynamic interaction of ribosome and translocon… 
2010
2010
Diverse Pathways for Maturation of the Na,K-ATPase β1 and β2 Subunits in the Endoplasmic Reticulum of Madin-Darby Canine Kidney Cells*
Proper folding of the Na,K-ATPase β subunits followed by assembly with the α subunits is necessary for their export from the… 
Highly Cited
2009
Highly Cited
2009
Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis.
Supplemental oxygen therapy (hyperoxia) in preterm babies with respiratory stress is associated with lung injury and the… 
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