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Glycosylphosphatidylinositol Diacylglycerol-Lyase

Known as: Phospholipase C, Glycosylphosphatidylinositol-Specific, Glycosylphosphatidylinositol Specific Phospholipase C, Phospholipase C, PtdIns-Glycan 
A type C phospholipase specific for GLYCOSYLPHOSPHATIDYLINOSITOLS. It plays a role in the breaking of GPI MEMBRANE ANCHORS.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BackgroundPhosphoinositide lipid kinases (PIKs) generate specific phosphorylated variants of phosatidylinositols (PtdIns) that… Expand
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Highly Cited
2009
Highly Cited
2009
Many diseases and disorders are characterized by quantitative and/or qualitative changes in complex carbohydrates. Mass… Expand
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Highly Cited
1999
Highly Cited
1999
We have investigated the organization, on the plasma membrane and in detergent‐insoluble membrane vesicles, of two neuronal… Expand
Highly Cited
1999
Highly Cited
1999
PrPC, the normal isoform of the prion component PrPSc, is a 33–35-kDa glycophosphatidylinositol-anchored glycoprotein expressed… Expand
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1999
1999
Covalent modification with lipid can target cytosolic proteins to biological membranes. With intrinsic membrane proteins, the… Expand
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Review
1998
Review
1998
  • A. Toker
  • Current opinion in cell biology
  • 1998
  • Corpus ID: 37575319
Phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) is a membrane phospholipid found in all eukaryotic cells which regulates… Expand
Highly Cited
1997
Highly Cited
1997
While many cell types express receptors for the Fc domain of IgG (FcγR), only primate polymorphonuclear neutrophils (PMN) express… Expand
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Highly Cited
1993
Highly Cited
1993
In simple epithelial cells, the delivery of apical and basolateral proteins to the cell surface is mediated by sorting in the… Expand
Highly Cited
1989
Highly Cited
1989
A novel cell surface antigen has been identified on a wide range of lymphoid cells and erythrocytes. A mAb YTH 53.1 (CD59… Expand
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Highly Cited
1986
Highly Cited
1986
A novel membrane-bound glycan-phosphatidylinositol-specific phospholipase C, which catalyzes the conversion of membrane form… Expand