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BackgroundPhosphoinositide lipid kinases (PIKs) generate specific phosphorylated variants of phosatidylinositols (PtdIns) that… Expand Many diseases and disorders are characterized by quantitative and/or qualitative changes in complex carbohydrates. Mass… Expand We have investigated the organization, on the plasma membrane and in detergent‐insoluble membrane vesicles, of two neuronal… Expand PrPC, the normal isoform of the prion component PrPSc, is a 33–35-kDa glycophosphatidylinositol-anchored glycoprotein expressed… Expand Covalent modification with lipid can target cytosolic proteins to biological membranes. With intrinsic membrane proteins, the… Expand Phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) is a membrane phospholipid found in all eukaryotic cells which regulates… Expand While many cell types express receptors for the Fc domain of IgG (FcγR), only primate polymorphonuclear neutrophils (PMN) express… Expand In simple epithelial cells, the delivery of apical and basolateral proteins to the cell surface is mediated by sorting in the… Expand A novel cell surface antigen has been identified on a wide range of lymphoid cells and erythrocytes. A mAb YTH 53.1 (CD59… Expand A novel membrane-bound glycan-phosphatidylinositol-specific phospholipase C, which catalyzes the conversion of membrane form… Expand