The role of pilin glycan in neisserial pathogenesis

  title={The role of pilin glycan in neisserial pathogenesis},
  author={Asesh Banerjee and Salil K. Ghosh},
  journal={Molecular and Cellular Biochemistry},
The pilus of pathogenic Neisseria is a polymer composed mainly of the glycoprotein, pilin. Recent investigations significantly enhanced characterization of pilin glycan (Pg) from N. gonorrhoeae (gonococcus, GC) and N. meningitidis (meningococcus, MC). Several pilin glycosylation genes were discovered recently from these bacteria and some of these genes transfer sugars previously unknown to be present in neisserial pili. Due to these findings, glycans of GC and MC pilin are now considered more… CONTINUE READING


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