Genetic Heterogeneity

Known as: Heterogeneities, Genetic, Genetic Heterogeneities, Heterogeneous. 
The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1940-2017
0500100019402016

Papers overview

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Review
2016
Review
2016
Recent developments in massively parallel sequencing and digital genomic techniques support the clinical validity of cell-free… (More)
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Review
2015
Review
2015
Breast cancer is composed of multiple subtypes with distinct morphologies and clinical implications. The advent of microarrays… (More)
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Review
2015
Review
2015
Tumor cells able to recapitulate tumor heterogeneity have been tracked, isolated and characterized in different tumor types, and… (More)
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Highly Cited
2012
Highly Cited
2012
Despite the success of targeted therapies in the treatment of cancer, the development of resistance limits the ability to… (More)
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Highly Cited
2010
Highly Cited
2010
Strong evidence suggests that rare mutations of severe effect are responsible for a substantial portion of complex human disease… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Epidermal growth factor receptor (EGFR) antibody therapy is established in patients with wild-type KRAS colorectal… (More)
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Highly Cited
2009
Highly Cited
2009
CONTEXT Intratumoral heterogeneity of HER2 gene amplification has been well documented and represents subclonal diversity within… (More)
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Highly Cited
2003
Highly Cited
2003
The identification and characterization of genes that influence the risk of common, complex multifactorial diseases, primarily… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE Neonatal-onset multisystem inflammatory disease (NOMID; also known as chronic infantile neurologic, cutaneous… (More)
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Highly Cited
1993
Highly Cited
1993
Breast cancer is known to have an inherited component, consistent in some families with autosomal dominant inheritance; in such… (More)
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