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Genes, abl
Known as:
Gene, abl
, abl Gene
, abl Genes
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes…
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National Institutes of Health
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Related topics
Related topics
7 relations
Fusion Proteins, bcr-abl
Oncogene Proteins v-abl
Proto-Oncogene Proteins c-abl
aspects of radiation effects
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abl Oncogene
c-abl Proto-Oncogenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Arsenic trioxide inhibits translation of mRNA of bcr-abl, resulting in attenuation of Bcr-Abl levels and apoptosis of human leukemia cells.
R. Nimmanapalli
,
P. Bali
,
+5 authors
K. Bhalla
Cancer research
2003
Corpus ID: 14228435
Present studies demonstrate that treatment with arsenic trioxide (AT) lowered ectopically expressed or endogenous levels of Bcr…
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Highly Cited
1999
Highly Cited
1999
Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes).
Y. Wu
,
L. Yu
,
R. McMahon
,
J. Rossi
,
S. Forman
,
D. Snyder
Human gene therapy
1999
Corpus ID: 7598364
Deoxyribozymes, or DNA enzymes (DNAzymes), are novel nucleic acids that have the ability to bind to specific sequences of RNA…
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Highly Cited
1991
Highly Cited
1991
Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.
J. Mcwhirter
,
J. Wang
Molecular and cellular biology
1991
Corpus ID: 12322695
Chronic myelogenous leukemia and one type of acute lymphoblastic leukemia are characterized by a 9;22 chronosome translocation in…
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Highly Cited
1990
Highly Cited
1990
Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization
D. Tkachuk
,
C. Westbrook
,
+7 authors
D. Pinkel
Science
1990
Corpus ID: 23929214
Chronic myelogeneous leukemia (CML) is genetically characterized by fusion of the bcr and abl genes on chromosomes 22 and 9…
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Highly Cited
1988
Highly Cited
1988
Detection of minimal residual bcr/abl transcripts by a modified polymerase chain reaction.
M. Lee
,
K. Chang
,
+4 authors
S. Stass
Blood
1988
Corpus ID: 1409917
The Philadelphia (Ph1) chromosome in chronic myelogenous leukemia (CML) involves reciprocal translocation of the bcr gene and the…
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Highly Cited
1987
Highly Cited
1987
The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia.
A. Bernards
,
C. Rubin
,
C. Westbrook
,
M. Paskind
,
D. Baltimore
Molecular and cellular biology
1987
Corpus ID: 42838779
The c-abl protooncogene is unusual in two respects; it has multiple, widely space N-terminal coding exons transcribed by…
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Highly Cited
1987
Highly Cited
1987
Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia
A. Hermans
,
N. Heisterkamp
,
+7 authors
G. Grosveld
Cell
1987
Corpus ID: 16186568
Highly Cited
1987
Highly Cited
1987
Molecular characterization of the testis specific c‐abl mRNA in mouse.
D. Meijer
,
A. Hermans
,
+7 authors
G. Grosveld
The EMBO journal
1987
Corpus ID: 45717917
The c‐abl gene encodes a protein tyrosine kinase and is transcribed from at least two promoters giving rise to transcripts of two…
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Highly Cited
1986
Highly Cited
1986
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene
E. Shtivelman
,
B. Lifshitz
,
R. Gale
,
B. Roe
,
E. Canaani
Cell
1986
Corpus ID: 36324337
Highly Cited
1984
Highly Cited
1984
The mouse c-abl locus: Molecular cloning and characterization
J. Y. Wang
,
F. Ledley
,
S. Goff
,
Rosalind C. Lee
,
Y. Groner
,
D. Baltimore
Cell
1984
Corpus ID: 40119722
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