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Proto-Oncogene Proteins c-abl

Known as: c abl Proteins, abl Proto Oncogene Proteins, Proto Oncogene Proteins abl 
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis, is an obligate intracellular bacterium of granulocytes… Expand
Review
2001
Review
2001
Recent investigations have rapidly added crucial new insights into the complex functions of the normal BCR gene and of the BCR… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The Bcr-Abl tyrosine kinase constitutively activates cytokine signal transduction pathways that stimulate growth and… Expand
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Highly Cited
2000
Highly Cited
2000
A search for c-Abl interacting proteins resulted in the recovery of PSTPIP1, originally identified as a binding protein of the… Expand
Highly Cited
1999
Highly Cited
1999
Signal transducers and activators of transcription (STATs) belong to a family of transcription factors that were originally… Expand
Highly Cited
1998
Highly Cited
1998
The ubiquitously expressed nonreceptor tyrosine kinase c-Abl contains three nuclear localization signals, however, it is found in… Expand
Highly Cited
1997
Highly Cited
1997
The c-Jun amino-terminal kinase (JNK) is a member of the stress-activated group of mitogen-activated protein (MAP) kinases that… Expand
Highly Cited
1995
Highly Cited
1995
A novel cellular protein, Abl-interactor-1 (Abi-1), which specifically interacts with the carboxy-terminal region of Abl… Expand
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Highly Cited
1991
Highly Cited
1991
BCR-ABL is a chimeric oncogene implicated in the pathogenesis of Philadelphia chromosome-positive human leukemias. BCR first exon… Expand
Highly Cited
1985
Highly Cited
1985
The Philadelphia chromosome (Ph1), observed in greater than 90% of chronic myelogenous leukemia (CML) patients, results from a… Expand