Proto-Oncogene Proteins c-abl

Known as: c abl Proteins, abl Proto Oncogene Proteins, Proto Oncogene Proteins abl 
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis, is an obligate intracellular bacterium of granulocytes… (More)
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Highly Cited
2006
Highly Cited
2006
Intracellular signaling molecules and apoptotic factors seem to play an important role in determining the radiation response of… (More)
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Highly Cited
2000
Highly Cited
2000
The Bcr-Abl tyrosine kinase constitutively activates cytokine signal transduction pathways that stimulate growth and prevent… (More)
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Highly Cited
2000
Highly Cited
2000
A search for c-Abl interacting proteins resulted in the recovery of PSTPIP1, originally identified as a binding protein of the… (More)
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Highly Cited
1999
Highly Cited
1999
c-Abl, a non-receptor tyrosine kinase, is activated by agents that damage DNA. This activation results in either arrest of the… (More)
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Highly Cited
1998
Highly Cited
1998
The ubiquitously expressed nonreceptor tyrosine kinase c-Abl contains three nuclear localization signals, however, it is found in… (More)
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Highly Cited
1997
Highly Cited
1997
The c-Jun amino-terminal kinase (JNK) is a member of the stress-activated group of mitogen-activated protein (MAP) kinases that… (More)
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Highly Cited
1995
Highly Cited
1995
A novel cellular protein, Abl-interactor-1 (Abi-1), which specifically interacts with the carboxy-terminal region of Abl… (More)
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Highly Cited
1992
Highly Cited
1992
The hallmark of chronic myelogenous leukemia is the translocation of the human c-abl protooncogene (ABL) from chromosome 9 to the… (More)
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Highly Cited
1991
Highly Cited
1991
BCR-ABL is a chimeric oncogene implicated in the pathogenesis of Philadelphia chromosome-positive human leukemias. BCR first exon… (More)
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