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GZMA protein, human

Known as: Granzyme 1, human T cell-associated serine proteinase, H Factor 
Granzyme A (262 aa, ~29 kDa) is encoded by the human GZMA gene. This protein plays a role in both proteolysis and apoptosis.
National Institutes of Health

Related topics

Related topics

14 relations
Cell-Mediated CytolysisCytotoxic T-LymphocytesEnzyme GeneGZMA gene

Broader (2)

Granzymesgranzyme A

Papers overview

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Highly Cited
2011
Highly Cited
2011
HF‐Based Etching Processes for Improving Laser Damage Resistance of Fused Silica Optical Surfaces
The effect of various HF-based etching processes on the laser damage resistance of scratched fused silica surfaces has been… 
Highly Cited
2011
Highly Cited
2011
SERCA2a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure
Background—Sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) gene therapy improves mechanical function in heart failure and is… 
Highly Cited
2006
Highly Cited
2006
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.
Highly Cited
2006
Highly Cited
2006
Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.
We have recently shown that RyR2 (cardiac ryanodine receptor) is phosphorylated by PKA (protein kinase A/cAMP-dependent protein… 
Highly Cited
2002
Highly Cited
2002
Plasma Urotensin in Human Systolic Heart Failure
Background—Human urotensin II (UTN) has potent vasoactive and cardiostimulatory effects, acting on the G protein–linked receptor… 
Highly Cited
2001
Highly Cited
2001
Organic/inorganic hybrid composites from cubic silsesquioxanes.
A new class of epoxy nanocomposites with completely defined organic/inorganic phases was prepared by reacting octakis… 
Review
2001
Review
2001
The Impact of Cardiac Natriuretic Peptide Determination on the Diagnosis and Management of Heart Failure
Abstract The long-predicted endocrine function of the heart has been proven by the discovery of atrial natriuretic peptide… 
Highly Cited
1999
Highly Cited
1999
The Brucella abortus host factor I (HF‐I) protein contributes to stress resistance during stationary phase and is a major determinant of virulence in mice
Brucella abortus is a facultative intracellular pathogen that causes abortion and infertility in domestic animals and a severe… 
Highly Cited
1996
Highly Cited
1996
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia.
Cytolytic lymphocytes are of cardinal importance in the recovery from primary viral infections. Both natural killer cells and… 
Highly Cited
1994
Highly Cited
1994
Regulation of the Escherichia coli hfq gene encoding the host factor for phage Q beta
The host factor (HF-I) for phage Q beta RNA replication is a small protein of 102 amino acid residues encoded by the hfq gene at… 
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