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GTPase-Activating Proteins

Known as: GTPase activating protein, GTPase-Activating Proteins [Chemical/Ingredient], GTPase Activating Proteins 
An extensive family of proteins that stimulates the GTPase activity of both heterotrimeric G proteins and GTP-binding ras-superfamily proteins.
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (34)

ARAP1 protein, humanARHGAP20 protein, humanARHGAP26 protein, humanARHGAP5 protein, human
ARHGAP35 protein, humanGAPVD1 geneGTPase activator activityIn Blood

Broader (2)

GTP Phosphohydrolase ActivatorsProteins

Papers overview

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Review
2012
Review
2012
Rac signaling in breast cancer: a tale of GEFs and GAPs.
Highly Cited
2011
Highly Cited
2011
Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins
Review
2006
Review
2006
RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins.
Highly Cited
2001
Highly Cited
2001
Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.
The role of prenylation in the interaction of Rho-family small GTPases with their GTPase activating proteins (GAPs) was… 
Highly Cited
2000
Highly Cited
2000
The semaphorin 3A receptor may directly regulate the activity of small GTPases
Highly Cited
2000
Highly Cited
2000
Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Highly Cited
1997
Highly Cited
1997
Isolation and Characterization of a GTPase Activating Protein Specific for the Rab3 Subfamily of Small G Proteins*
The Rab small G protein family, consisting of nearly 30 members, is implicated in intracellular vesicle trafficking. They cycle… 
Highly Cited
1992
Highly Cited
1992
Association between GTPase activators for Rho and Ras families
THE ras-related low-molecular-mass GTPases participate in signal transduction involving a variety of cellular functions… 
Highly Cited
1990
Highly Cited
1990
PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex
Highly Cited
1988
Highly Cited
1988
Purification of ras GTPase activating protein from bovine brain.
In cytosolic extracts of bovine brain, we detected ras GTPase activating protein (GAP) activity that stimulated the GTP… 
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