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GTPase-Activating Proteins
Known as:
GTPase activating protein
, GTPase-Activating Proteins [Chemical/Ingredient]
, GTPase Activating Proteins
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An extensive family of proteins that stimulates the GTPase activity of both heterotrimeric G proteins and GTP-binding ras-superfamily proteins.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (34)
ARAP1 protein, human
ARHGAP20 protein, human
ARHGAP26 protein, human
ARHGAP5 protein, human
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ARHGAP35 protein, human
GAPVD1 gene
GTPase activator activity
In Blood
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Broader (2)
GTP Phosphohydrolase Activators
Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
Lynne Chantranupong
,
Sonia M. Scaria
,
+7 authors
D. Sabatini
Cell
2016
Corpus ID: 14605958
Highly Cited
2005
Highly Cited
2005
The HMG-CoA Reductase Inhibitor Lovastatin Reverses the Learning and Attention Deficits in a Mouse Model of Neurofibromatosis Type 1
Weidong Li
,
Yijun Cui
,
+5 authors
Alcino J. Silva
Current Biology
2005
Corpus ID: 12826598
Highly Cited
2003
Highly Cited
2003
Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb
A. Tee
,
B. Manning
,
Philippe P Roux
,
L. Cantley
,
J. Blenis
Current Biology
2003
Corpus ID: 6519150
Review
2002
Review
2002
Guanine nucleotide exchange factors for Rho GTPases: turning on the switch.
A. Schmidt
,
A. Hall
Genes & development
2002
Corpus ID: 31994290
Rho GTPases control many aspects of cell behavior through the regulation of multiple signal transduction pathways (Van Aelst and…
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Highly Cited
2001
Highly Cited
2001
Signal Transduction in Neuronal Migration Roles of GTPase Activating Proteins and the Small GTPase Cdc42 in the Slit-Robo Pathway
Kit Wong
,
X. Ren
,
+10 authors
Y. Rao
Cell
2001
Corpus ID: 2458943
Review
1998
Review
1998
Structure and function in GroEL-mediated protein folding.
P. Sigler
,
Z. Xu
,
H. Rye
,
S. Burston
,
W. Fenton
,
A. Horwich
Annual review of biochemistry
1998
Corpus ID: 229871
Recent structural and biochemical investigations have come together to allow a better understanding of the mechanism of…
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Highly Cited
1996
Highly Cited
1996
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
G. Bollag
,
D. Clapp
,
+8 authors
K. Shannon
Nature Genetics
1996
Corpus ID: 19547523
Individuals with neurofibromatosis type 1 (NF1) are predisposed to certain cancers including juvenile chronic myelogenous…
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Highly Cited
1992
Highly Cited
1992
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
W. Fantl
,
J. Escobedo
,
+4 authors
L. Williams
Cell
1992
Corpus ID: 34434246
Highly Cited
1992
Highly Cited
1992
Association between GTPase activators for Rho and Ras families
J. Settleman
,
C. Albright
,
L. Foster
,
R. Weinberg
Nature
1992
Corpus ID: 4271554
THE ras-related low-molecular-mass GTPases participate in signal transduction involving a variety of cellular functions…
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Highly Cited
1991
Highly Cited
1991
cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product.
D. Marchuk
,
A. Saulino
,
+7 authors
F. Collins
Genomics
1991
Corpus ID: 30556324
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