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GTPase activator activity

Known as: Ran GAP activity, RanGAP, GAP activity 
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. [GOC:mah]
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
The hexanucleotide repeat expansion (HRE) GGGGCC (G4C2) in C9orf72 is the most common cause of amyotrophic lateral sclerosis (ALS… Expand
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Highly Cited
2013
Highly Cited
2013
Background: The interaction of the potato disease resistance protein Rx with RanGAP2 is important for virus resistance. Results… Expand
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Highly Cited
2008
Highly Cited
2008
In higher plants, the plane of cell division is faithfully predicted by the preprophase band (PPB). The PPB, a cortical ring of… Expand
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Highly Cited
2008
Highly Cited
2008
Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and… Expand
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Highly Cited
2007
Highly Cited
2007
Nucleotide binding leucine-rich repeat (NB-LRR) proteins play an important role in plant and mammalian innate immunity. In plants… Expand
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Highly Cited
2007
Highly Cited
2007
The Ran GTPase controls multiple cellular processes including nucleocytoplasmic transport, spindle assembly, and nuclear envelope… Expand
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Highly Cited
2007
Highly Cited
2007
Race-specific disease resistance in plants is mediated by the products of host disease resistance (R) genes. Plant genomes… Expand
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Highly Cited
2002
Highly Cited
2002
GTPase-activating proteins (GAPs) increase the rate of GTP hydrolysis on guanine nucleotide-binding proteins by many orders of… Expand
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Highly Cited
1999
Highly Cited
1999
Segregation Distorter (SD) in Drosophila melanogaster is a naturally occurring meiotic drive system in which the SD chromosome is… Expand
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Highly Cited
1995
Highly Cited
1995
RCC1 (the regulator of chromosome condensation) stimulates guanine nucleotide dissociation on the Ras-related nuclear protein Ran… Expand
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